Textbook of Clinical Trials, Second Edition

Textbook of Clinical Trials, Second Edition

Editor(s): David Machin, Simon Day, Sylvan Green

Published Online: 17 MAY 2007

Print ISBN: 9780470010143

Online ISBN: 9780470010167

DOI: 10.1002/9780470010167

About this Book

Now published in its Second Edition, the Textbook of Clinical Trials offers detailed coverage of trial methodology in diverse areas of medicine in a single comprehensive volume.

Praise for the First Edition:

"... very useful as an introduction to clinical research, or for those planning specific studies within therapeutic or disease areas." BRITISH JOURNAL OF SURGERY, Vol. 92, No. 2, February 2005

The book's main concept is to describe the impact of clinical trials on the practice of medicine. It separates the information by therapeutic area because the impact of clinical trials, the problems encountered, and the numbers of trials in existence vary tremendously from specialty to specialty. The sections provide a background to the disease area and general clinical trial methodology before concentrating on particular problems experienced in that area.  Specific examples are used throughout to address these issues.

The Textbook of Clinical Trials, Second Edition

  • Highlights the various ways clinical trials have influenced the practice of medicine in many therapeutic areas
  • Describes the challenges posed by those conducting clinical trials over a range of medical specialities and allied fields
  • Additional therapeutic areas are included in this Second Edition to fill gaps in the First Edition as the number and complexity of trials increases in this rapidly developing area
  • Newly covered or updated in the Second Edition: general surgery, plastic surgery, aesthetic surgery, palliative care, primary care, anaesthesia and pain, transfusion, wound healing, maternal and perinatal health, early termination, organ transplants, ophthalmology, epilepsy, infectious disease, neuro-oncology, adrenal, thyroid and urological cancers, as well as a chapter on the Cochrane network

Table of contents

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  1. Introduction

  2. Cancer

    1. Chapter 4

      Breast Cancer (pages 47–61)

      Donald A. Berry, Terry L. Smith and Aman U. Buzdar

    2. Chapter 5

      Childhood Cancer (pages 63–80)

      Sharon B Murphy and Jonathan J. Shuster

    3. Chapter 6

      Gastrointestinal Cancers (pages 81–104)

      Daniel Sargent, Richard Goldberg and Paul Limburg

    4. Chapter 7

      Melanoma (pages 105–119)

      Ping-Yu Liu and Vernon K. Sondak

    5. Chapter 10

      Thyroid Cancer (pages 143–148)

      Vijayaraman Arutchelvam and Petros Perros

    6. Chapter 11

      Urologic Cancers (pages 149–165)

      Edith D. Canby-Hagino, Catherine M. Tangen and Ian M. Thompson

  3. Cardiology

  4. Dentistry and Oral Health Care

    1. Chapter 15

      Dentistry and Oral Health Care (pages 241–259)

      May C.M. Wong, Colman McGrath and Edward C.M. Lo

  5. Dermatology

  6. Infectious Diseases

  7. Ophthalmology

    1. Chapter 19

      Ophthalmology (pages 317–331)

      Jonathan C.K. Clarke and Peng-Tee Khaw

  8. Psychiatry

    1. Chapter 20

      Anxiety Disorders (pages 333–351)

      M. Katherine Shear and Philip W. Lavori

  9. Reproductive Health

    1. Chapter 23

      Contraception (pages 395–419)

      Gilda Piaggio and Timothy M. M. Farley

    2. Chapter 26

      Maternal and Perinatal Health (pages 459–473)

      José Villar, Allan Donner, Edgardo Abalos and Liana Campódonico

  10. Respiratory

  11. Surgery & Anaesthesia

  12. Transplantation

  13. Other Procedures

  14. Special Populations

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