Cancer Vaccines and Tumor Immunity

Copyright © 2008 John Wiley & Sons, Inc.

Cancer Vaccines and Tumor Immunity

Editor(s): Rimas Orentas, James W. Hodge, Bryon D. Johnson

Published Online: 1 MAR 2007

Print ISBN: 9780470074749

Online ISBN: 9780470170113

DOI: 10.1002/9780470170113

About this Book

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About The Product

Cancer Vaccines and Tumor Immunity offers a review of the basic scientific discoveries that have moved forward into clinical trials. Presented in the context of real-world human research and experimentation, these major scientific advances demonstrate how our understanding of immune activation, T-regulatory cells, and autoimmunity will impact cancer vaccine design. The authors also explain how vaccination in the context of bone marrow transplantation will open new avenues for clinical study in the future.

Table of contents

    1. You have free access to this content
      Frontmatter (pages i–xvi)

  2. Part I: Introduction

    1. Chapter 1

      Cancer Vaccines: Progress and Promise (pages 1–11)

      Rimas J. Orentas, Bryon Johnson and James Hodge

  3. Part II: Adjuvant Therapy: Enhancing the Endogenous Immune Response

    1. Chapter 2

      Fully Synthetic Carboyhydrate-Based Antitumor Vaccines (pages 13–27)

      Rebecca M. Wilson and Samuel J. Danishefsky

    2. Chapter 3

      Bacillus Calmette–Guérin Immunotherapy of Genitourinary Cancer (pages 29–42)

      Donald L. Lamm

    3. Chapter 4

      Stimulation of Toll-Like Receptor 9 for Enhancing Vaccination (pages 43–66)

      Daniel E. Speiser and Arthur M. Krieg

  4. Part III: Antigen-Specific Therapy: Novel Presentation of Peptide and Protein Antigens

    1. Chapter 5

      Polyepitope Vaccines (pages 67–78)

      Corey Smith and Rajiv Khanna

    2. Chapter 6

      Antigen-Specific Cancer Immunotherapy: HPV-Associated Cervical Cancer as a Model System (pages 79–94)

      Shaw-Wei D. Tsen, Chien-Fu Hung and T.-C. Wu

    3. Chapter 7

      Poxviral Vectors for Cancer Vaccines: State of the Art (pages 95–111)

      Elizabeth K. Wansley

    4. Chapter 8

      Immunotherapeutic Strategies against Cancer using Listeria monocytogenes as a Vector for Tumor Antigens (pages 113–129)

      Nicholas C. Souders, Thorsten Verch and Yvonne Paterson

    5. Chapter 9

      Coupling Innate and Adaptive Immunity with Yeast-Based Cancer Immunotherapy (pages 131–149)

      Sibyl Munson, Joanne Parker, Thomas H. King, Yingnian Lu, Victoria Kelley, Zhimin Guo, Virginia Borges and Alex Franzusoff

  5. Part IV: Cell-Based Therapy: Using Cancer Cells as a Means to Induce Specific Tumor Immunity

    1. Chapter 10

      Allogeneic Whole-Cell Vaccines (pages 151–167)

      John Copier and Angus Dalgleish

    2. Chapter 11

      Jump-Starting Tumor Immunity with Breast Cancer Therapeutics (pages 169–187)

      Leisha A. Emens

    3. Chapter 12

      T-Regulatory Cell Manipulation in Tumor Immunotherapy (pages 189–204)

      Jens Rüter, Brian G. Barnett, Ilona Kryczek, Michael J. Brumlik, Benjamin J. Daniel, George Coukos, Weiping Zou and Tyler J. Curiel

    4. Chapter 13

      Tumor Vaccination after Autologous HSCT: What has been Learned from Experimental Models (pages 205–215)

      Weiqing Jing and Bryon D. Johnson

    5. Chapter 14

      Vaccines in the Setting of Hematopoietic Stem Cell Transplantation (pages 217–228)

      Ronald Gress and Claude Sportes

    6. Chapter 15

      Intratumor Generation of Vigorous Antitumor Immune Responses (pages 229–242)

      Ping Yu and Yang-Xin Fu

    7. Chapter 16

      Cancer Immunotherapy: Untapping the Potential of Costimulatory Molecules Beyond CTLA-4 (pages 243–268)

      Mathew Augustine and Lieping Chen

  6. Part V: Defining Effective Clinical Responses

    1. Chapter 17

      Advances in Immune Monitoring Strategies for Cancer Vaccines and Immunotherapy (pages 269–289)

      Seunghee Kim-Schulze, Moshe Ornstein and Howard L. Kaufman

    2. Chapter 18

      Immune Evaluation of Cancer Vaccines (pages 291–307)

      Theresa L. Whiteside

    1. You have free access to this content
      Index (pages 309–334)

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