RNA and DNA Editing: Molecular Mechanisms and Their Integration into Biological Systems

Copyright © 2008 John Wiley & Sons, Inc.

RNA and DNA Editing: Molecular Mechanisms and Their Integration into Biological Systems

Editor(s): Harold C. Smith

Published Online: 7 SEP 2007

Print ISBN: 9780470109915

Online ISBN: 9780470262269

DOI: 10.1002/9780470262269

About this Book

Product Information

About The Product

RNA and DNA Editing assembles a team of leading experts who present the latest discoveries in the field alongside the latest models and methodology. In addition, the authors set forth the many open questions and suggest routes for further investigation. Overall, the book serves as a practical guide for professionals in the field who need to understand the interrelationship of RNA and DNA editing with other chemical and biological processes.

Table of contents

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      Frontmatter (pages i–xxiii)

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      Color Plates (pages c1–c12)

  3. Part I: Diversification of the Proteome through RNA and DNA Editing

    1. Chapter 1

      Diversifying Exon Code through A-to-I RNA Editing (pages 1–30)

      Willemijn M. Gommans, Dylan E. Dupuis, Jill E. McCane, Nicholas E. Tatalias and Stefan Maas

    2. Chapter 2

      Antibody Gene Diversification by Aid-Catalyzed DNA Editing (pages 31–70)

      Donna A. MacDuff, Steven M. Offer, Zachary L. Demorest and Reuben S. Harris

    3. Chapter 3

      Protein–Protein and RNA–Protein Interactions in U-Insertion/Deletion RNA Editing Complexes (pages 71–98)

      Jorge Cruz-Reyes and Alfredo Hernandez

    4. Chapter 4

      Machinery of RNA Editing in Plant Organelles (pages 99–119)

      Toshiharu Shikanai and Jun-ichi Obokata

  4. Part II: Functional Coordination of RNA Editing with other Cellular Mechanisms

    1. Chapter 5

      Transfer RNA Editing Enzymes; At the Crossroads of Affinity and Specificity (pages 121–145)

      Juan D. Alfonzo and F. Nina Papavasiliou

    2. Chapter 6

      A-to-I Editing as a Co-Transcriptional RNA Processing Event (pages 146–161)

      Marie Öhman

    3. Chapter 7

      Studying and Working with Ribonucleoproteins that Catalyze H/ACA Guided RNA Modification (pages 162–174)

      U. Thomas Meier

    4. Chapter 8

      Functional Roles of Spliceosomal SNRNA Modifications in Pre-MRNA Splicing (pages 175–189)

      David Stephenson, John Karijolich and Yi-Tao Yu

    5. Chapter 9

      A Role for A-to-I Editing in Gene Silencing (pages 190–202)

      Jing Zhou, Ling-Ling Chen and Gordon G. Carmichael

    6. Chapter 10

      Biological Implications and Broader-Range Functions for APOBEC-1 and APOBEC-1 Complementation Factor (ACF) (pages 203–230)

      Valerie Blanc and Nicholas O. Davidson

    7. Chapter 11

      Antiviral Function of APOBEC3 Cytidine Deaminases (pages 231–254)

      Ann M. Sheehy

  5. Part III: Predictive Structures

    1. Chapter 12

      A-to-I Editing of ALU Repeats (pages 255–279)

      Eli Eisenberg and Erez Y. Levanon

    2. Chapter 13

      RNA Editing in Dinoflagellates and its Implications for the Evolutionary History of the Editing Machinery (pages 280–309)

      Senjie Lin, Huan Zhang and Michael W. Gray

  6. Part IV: Structural Approaches

    1. Chapter 14

      The Box C/D RNPS: Evolutionarily Ancient Nucleotide Modification Complexes (pages 311–339)

      Keith Gagnon, Xinxin Zhang and E. Stuart Maxwell

    2. Chapter 15

      Structural Features of the ADAR Family of Enzymes and their Substrates (pages 340–368)

      M. Wadud Bhuiya, Evan M. Rittery and Bernard A. Brown

    3. Chapter 16

      Chemistry, Phylogeny, and Three-Dimensional Structure of the APOBEC Protein Family (pages 369–419)

      Celeste MacElrevey and Joseph E. Wedekind

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      Index (pages 421–426)

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