Phycotoxins: Chemistry and Biochemistry

Phycotoxins: Chemistry and Biochemistry

Editor(s): Luis M. Botana

Published Online: 30 NOV 2007

Print ISBN: 9780813827001

Online ISBN: 9780470277874

DOI: 10.1002/9780470277874

About this Book

Phycotoxins: Chemistry and Biochemistry presents the most updated information available on phycotoxins. Major emphases are given to chemistry and biochemistry, while minor emphases are given to the aspects of origin, toxicology, or analytical methodology. The book discusses 16 phycotoxins, 7 on those affecting the nervous systems, 4 affecting other body systems; and 4 with undefined targets.

An alphabetical listing of toxins presented includes: Azaspiracids; Brevetoxins; Cyanobacterial toxins; Domoic acid; Gambierols; Gymnodimines, prorocentrolides, spirolides, pinnatoxins and cyclic imines in general; Maitotoxin; Okadaic acid and dinophysistoxins; Palytoxins and ostreocins; Pectenotoxins; Polycavernosides; and Yessotoxins. In addition, several mechanistic aspects of newer or emerging toxins are covered such as amphidinols or gymnocine. Information presented and coverage of each toxin follows the following distribution: background and toxicology (10%); chemistry, biochemistry and metabolism (75%); mechanism of action (10%); and analytical methodology (5%).

The detailed information on chemistry in Phycotoxins: Chemistry and Biochemistry provides investigators, regulators, food technologists and toxicologists an updated basis on which research in other areas such as toxicology, mechanism of action, analytical methodology and pharmacology can be successfully developed and expanded.

Table of contents

    1. You have free access to this content
    2. Chapter 1

      Gambierol (pages 1–18)

      Makoto Sasaki, Eva Cagide and M. Carmen Louzao

    3. Chapter 2

      Brevetoxins: Structure, Toxicology, and Origin (pages 19–46)

      Ambrose Furey, Javier García, Keith O'Callaghan, Mary Lehane, Mónica Fernández Amandi and Kevin J. James

    4. Chapter 4

      Biochemistry of Maitotoxin (pages 55–73)

      Laura A. de la Rosa, Emilio Alvarez-Parrilla and Alejandro Martínez-Martínez

    5. Chapter 8

      Anatoxin-a and Analogues: Discovery, Distribution, and Toxicology (pages 141–158)

      Kevin J. James, Janet Crowley, Justine Duphard, Mary Lehane and Ambrose Furey

    6. Chapter 16

      Structural Assignment and Total Synthesis of Azaspiracid-1 (pages 397–409)

      Michael O. Frederick, Kevin P. Cole, Goran Petrovic, Eriketi Loizidou and K. C. Nicolaou

    7. You have free access to this content