Structure, Function, and Modulation of Neuronal Voltagegated Ion Channels

Structure, Function, and Modulation of Neuronal Voltagegated Ion Channels

Editor(s): Valentin K. Gribkoff, Leonard K. Kaczmarek

Published Online: 11 JUL 2008

Print ISBN: 9780471930136

Online ISBN: 9780470429907

DOI: 10.1002/9780470429907

About this Book

This book discusses voltage-gated ion channels and their importance in drug discovery and development. The book includes reviews of the channel genome, the physiological bases of targeting ion channels in disease, the unique technologies developed for ion channel drug discovery, and the increasingly important role of ion channel screening in cardiac risk assessment. It provides an important reference for research scientists and drug discovery companies.

Table of contents

    1. You have free access to this content
    1. You have free access to this content
  1. Part I: Neuronal Voltage-Gated Ion Channel Functions

  2. Part II: Modulatory Mechanisms and Influences on Neuronal Voltage-Gated Ion Channel Function

    1. Chapter 8

      Alternative Splicing of Neuronal Cav2 Calcium Channels (pages 217–250)

      Diane Lipscombe, Summer E. Allen, Annette C. Gray, Spiro Marangoudakis and Jesica Raingo

    2. Chapter 12

      BK Channels: Regulation of Expression and Physiological Impact (pages 317–342)

      Pallob Kundu, Abderrahmane Alioua, Yogesh Kumar, Rong Lu, Jimmy W. Ou, Enrique Sanchez-Pastor, Min Li, Enrico Stefani and Ligia Toro

  3. Part III: Drug Discovery Targets and Technology

    1. You have free access to this content

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