Process Scale Purification of Antibodies

Process Scale Purification of Antibodies

Editor(s): Uwe Gottschalk

Published Online: 15 AUG 2008

Print ISBN: 9780470209622

Online ISBN: 9780470444894

DOI: 10.1002/9780470444894

About this Book

Traditional column chromatography dominates current purification technology, and many of the productivity gains that have been achieved have relied on upscaling such devices. However, this comes with a cost penalty and the pharmaceutical industry has reached the point at which further upscaling becomes economically unsupportable. This book offers a broad-based reassessment of old and new purification methods, incorporating an analysis of innovative new trends in purification. The book has wide coverage of different antibody purification strategies and brings together top-tier experts to address problems in process-scale antibody purification.

Table of contents

    1. You have free access to this content
    2. Chapter 9

      Development of A Platform Process for the Purification of Therapeutic Monoclonal Antibodies (pages 187–201)

      Yuling Li, David W. Kahn, Olga Galperina, Erich Blatter, Robert Luo, Yaling Wu and Guihang Zhang

    3. Chapter 19

      Purification of Antibodies From Transgenic Plants (pages 387–406)

      Zivko L. Nikolov, Jeffrey T. Regan, Lynn F. Dickey and Susan L. Woodard

    4. You have free access to this content