Carbohydrate-Based Vaccines and Immunotherapies

Carbohydrate-Based Vaccines and Immunotherapies

Editor(s): Zhongwu Guo, Geert-Jan Boons

Published Online: 28 OCT 2008

Print ISBN: 9780470197561

Online ISBN: 9780470473283

DOI: 10.1002/9780470473283

Series Editor(s): Binghe Wang

About this Book

The fundamental science and the latest developments in carbohydrate-based vaccines

The relatively new field of glycoimmunology has emerged from the marriage of glycobiology and immunology, in recognition of the important role carbohydrates play as antigenic determinants. Carbohydrate-Based Vaccines and Immunotherapies comprehensively reviews the state of this exciting field, offering a single source for both the fundamental science and the latest developments.

With contributions by leading experts, this resource covers the design, synthesis, evaluation, and applications of various carbohydrate-based vaccines, including polysaccharides, neoglycoproteins, and neoglycolipids. The text approaches vaccine design from a chemical and molecular focus, staying in line with current advances.

Key topics covered by Carbohydrate-Based Vaccines and Immunotherapies include:

  • Recent developments towards clinically useful vaccines against bacteria, viruses, parasites, and fungi

  • Using adjuvants to improve immunogenicity and/or immunological properties of vaccines

  • Choosing and designing proper adjuvants for specific targets

  • Abnormal carbohydrates expressed by tumors

  • Carbohydrate-based therapeutic cancer vaccines or cancer immunotherapy

  • Clinical trials results for synthetic cancer vaccines

  • Glycoengineering of cell surface carborhydrates and its anticancer applications

  • Using cell surface carbohydrates for disease diagnosis

A single, convenient source of state-of-the-art information from leading authorities in the field, Carbohydrate-Based Vaccines and Immunotherapies is an essential reference for organic chemists and biochemists, academic researchers, and other students and professionals involved in vaccine design.

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