Ciba Foundation Symposium 129 - Autoimmunity and Autoimmune Disease

Ciba Foundation Symposium 129 - Autoimmunity and Autoimmune Disease

Editor(s): David Evered, Julie Whelm

Published Online: 28 SEP 2007

Print ISBN: 9780471910954

Online ISBN: 9780470513484

DOI: 10.1002/9780470513484

About this Book

This work focuses on the autoimmune processes that have now been proven to underlie a number of serious diseases, including diabetes mellitus, rheumatoid arthritis and multiple sclerosis. Papers explore the rapidly expanding developments in research on immune response and regulation, and their potential in the development of treatments for autoimmune diseases. The wide range of subjects covered here include: the nature of intracellular and cell surface-derived ``self'' antigens; competing theories of the generation of immune tolerance and their implications of current theories for research and treatment; possible links between autoimmunity and genetic complement deficiency; the contributions of interferons and class II HLA antigen expression to autoimmunity; and the potential of monoclonal antibodies and other biotechnological advances in treating human autoimmune conditions.

Table of contents

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    2. Cardiac Myosin and Autoimmune Myocarditis (pages 3–24)

      Noel R. Rose, Kirk W. Beisel, Ahvie Herskowitz, Nikolaus Neu, Luanne J. Wolfgram, Floria L. Alvarez, Monica D. Traystman and Susan W. Craig

    3. Molecular Basis for the Cross-Reactive Idiotypes on Human Anti-Igg Autoantibodies (Rheumatoid Factors) (pages 123–134)

      Dennis A. Carson, Pojen P. Chen, Thomas J. Kipps, Victor Radoux, Frank Jirik, Robert D. Goldfien, Robert I. Fox, Gregg J. Silverman and Sherman Fong

    4. Monoclonal Antibodies for the Depletion of Specific Subpopulations of Lymphocytes (pages 194–208)

      Herman Waldmann, Steve Cobbold, Shixin Qin, Richard Benjamin, Tony Nash, Jane Welsh and Georgia Tarnesby

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