Ciba Foundation Symposium 157 - Clinical Applications of TGF-β

Ciba Foundation Symposium 157 - Clinical Applications of TGF-β

Editor(s): Gregory R. Bock, Joan Marsh

Published Online: 28 SEP 2007

Print ISBN: 9780471928119

Online ISBN: 9780470514061

DOI: 10.1002/9780470514061

About this Book

TGF-beta, originally identified as a transforming growth factor with similar properties, is now known to exist as a family of factors with similar properties. These factors promote cell proliferation in some tissue types or conditions and induce cell differentiation in others. Features the latest information on the TGF-beta family and its receptors. Describes correlations between TGF-beta and certain cancers, including glioblastomas. Also contains reports of preliminary investigations of clinical applications for TGF-beta in many diseases, including leukemia and its use to accelerate wound healing.

Table of contents

    1. You have free access to this content
    2. Multiple Forms of TGF-β: Distinct Promoters and Differential Expression (pages 7–28)

      Anita B. Roberts, Seong-Jin Kim, Takafumi Noma, Adam B. Glick, Robert Lafyatis, Robert Lechleider, Sonia B. Jakowlew, Andrew Geiser, Michael A. O'Reilly, David Danielpour and Michael B. Sporn

    3. TGF-β: A Possible Autocrine Immune Regulator (pages 98–114)

      Catherine Lucas, Susan Wallick, Brian M Fendly, Irene Figari and Michael A. Palladino

    4. Effects of TGF-βs in the Liver: Cell Proliferation and Fibrogenesis (pages 165–177)

      Nelson Fausto, Janet E. Mead, Phillip A. Gruppuso, Alberto Castilla and Sonia B. Jakowlew

    5. Role of TGF-β1 in Experimental Glomerulonephritis (pages 178–193)

      Wayne A. Border, Seiya Okuda, Takamichi Nakamura, Lucia R. Languino and Erkki Ruoslahti

    6. In vivo and in vitro Effects of TGF-β1 on Normal and Neoplastic Haemopoiesis (pages 212–231)

      Francis W. Ruscetti, Claire Dubois, Lydia A. Falk, Sten E. Jacobsen, Garwin Sing, Dan L. Longo, Robert H. Wiltrout and Jonathan R. Keller

    7. You have free access to this content
    8. You have free access to this content