Ciba Foundation Symposium 158 - Host-Guest Molecular Interactions: From Chemistry to Biology

Copyright © Ciba Foundation 1991

Ciba Foundation Symposium 158 - Host-Guest Molecular Interactions: From Chemistry to Biology

Editor(s): Derek J. Chadwick, Kate Widdows

Published Online: 28 SEP 2007

Print ISBN: 9780471929581

Online ISBN: 9780470514085

DOI: 10.1002/9780470514085

About this Book

Product Information

About The Product

Composed of contributions from experts in the chemical and biological sciences, it explores host-guest molecular interactions leading to the formation of molecular assemblies containing two or more species. Exciting applications are emerging in this field and it is expected that improved understanding of the interactions in synthetic host molecule complexes will lead to a better understanding of the more complex biological systems. Topics include biomimetic chemistry, preorganization, self-assembly, template-directed synthesis, antibiotic binding to peptides and DNA, interactions between proteins and other molecules.

Table of contents

    1. You have free access to this content
      Front Matter (pages i–ix)

    2. Introduction (pages 1–4)

      Ian Sutherland

    3. Molecular Self-Assembly Processes (pages 5–22)

      J. Fraser Stoddart

    4. Self-Assembly in Supramolecular Systems (pages 23–41)

      George W. Gokel

    5. Host-Guest Interactions in Thin Membranes: Selective Ion Transport and Transduction into Electronic Signals (pages 42–54)

      D. N. Reinhoudt, W. F. Nijenhuis and P. D. van der Wal

    6. Molecular Recognition and Molecular Sensors (pages 55–72)

      W. John Albery

    7. The Natural Design of Vancomycin Family Antibiotics to Bind their Target Peptides (pages 73–97)

      Jonathan P. Waltho and Dudley H. Williams

    8. Clefts as Receptor and Enzyme Analogues (pages 98–114)

      Julius Rebek

    9. Enzyme Mimics (pages 115–127)

      Ronald Breslow

    10. Binding of Antibiotics to DNA (pages 128–146)

      Michael Waring

    11. Design of Sequence-Specific Bifunctional Nucleic Acid Ligands (pages 147–157)

      T. Montenay-Garestier, C. Hélène and N. T. Thuong

    12. Synthesis and Biochemical Studies of Dithioate DNA (pages 158–168)

      Marvin H. Caruthers, Graham Beaton, Lendell Cummins, Darla Graff, Yun-Xi Ma, William S. Marshall, Henri Sasmor, Paula Norris and Eric K. Yau

    13. Conformational Flexibility and Protein Specificity (pages 169–186)

      G. C. K. Roberts

    14. Protein Design: Template-Assembled Synthetic Proteins (pages 187–212)

      Robert I. Carey, Karl-Heinz Altmann and Manfred Mutter

    15. Binding of Peptides to Proteins: An Exercise in Molecular Design (pages 213–230)

      Allen B. Edmundson, Debra L. Harris, Gordon Tribbick and H. Mario Geysen

    16. Involvement of Water in Host–Guest Interactions (pages 231–248)

      R. U. Lemieux, L. T. J. Delbaere, H. Beierbeck and U. Spohr

    17. Molecular Modelling Approaches to Host–Guest Complexes (pages 249–265)

      J. G. Vinter and M. R. Saunders

    18. Summing-Up (pages 266–268)

      Ian Sutherland

    19. You have free access to this content
      Index of Contributors (pages 269–270)

    20. You have free access to this content
      Subject Index (pages 271–278)

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