Ciba Foundation Symposium 159 - Catalytic Antibodies

Ciba Foundation Symposium 159 - Catalytic Antibodies

Editor(s): Derek J. Chadwick, Joan Marsh

Published Online: 28 SEP 2007

Print ISBN: 9780471929628

Online ISBN: 9780470514108

DOI: 10.1002/9780470514108

About this Book

Contains the presentations and discussions that took place during a symposium at the CIBA Foundation on October 1-3, 1990 on the subject of catalytic antibodies. The recognition that monoclonal antibodies can possess catalytic activity is a recent advance with profound ramifications for chemistry. In addition to their potential commercial applications as catalysts for reactions, for which there are no known enzymes, antibodies promise to provide valuable insight into the detailed mechanisms of biological catalysis and organic chemistry.

Table of contents

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    2. Structural Aspects of Antibodies and Antibody-Antigen Complexes (pages 13–39)

      Ian A. Wilson, Robyn L. Stanfield, James M. Rini, Jairo H. Arevalo, Ursula Schulze-Gahmen, Daved H. Fremont and Enrico A. Stura

    3. Catalytic Antibodies: A New Window on Protein Chemistry (pages 201–210)

      Colin J. Suckling, Catriona M. Tedford, George R. Proctor, Abedawn I. Khalaf, Laura M. Bence and William H. Stimson

    4. Expanded Transition State Analogues (pages 211–226)

      G. Michael Blackburn, Gillian Kingsbury, Sriyani Jayaweera and Dennis R. Burton

    5. Tritylase Antibodies (pages 227–245)

      Brent L. Iverson, Sheila A. Iverson, Katherine E. Cameron, Guiti K. Jahangiri, Dahna S. Pasternak and Richard A. Lerner

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