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Ciba Foundation Symposium 165 - Postimplantation Development in the Mouse

Copyright © Ciba Foundation 1992

Ciba Foundation Symposium 165 - Postimplantation Development in the Mouse

Editor(s): Derek J. Chadwick, Joan Marsh

Published Online: 28 SEP 2007

Print ISBN: 9780471933847

Online ISBN: 9780470514221

DOI: 10.1002/9780470514221

About this Book

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Examines the establishment of the germ layers and other cell lineages in the early embryo including details of cell movements during the beginning stages of primitive streak formation. Discusses patterns of gene expression during the development of such tissues as the limb bud, skeletal, muscle and the central nervous systems placing special emphasis on commitment to particular cell types. Although it concentrates on the mouse as an example of mammalian development--chick, amphibian and Drosophila embryogenesis are employed whenever these organisms are more applicable to the study of a particular problem.

Table of contents

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      Front Matter (pages i–x)

    2. Introduction (pages 1–2)

      Anne L. McLaren

    3. Clonal Analysis of Cell Fate During Gastrulation and Early Neurulation in the Mouse (pages 3–26)

      K. A. Lawson and R. A. Pedersen

    4. Establishment and Organization of Germ Layers in the Gastrulating Mouse Embryo (pages 27–60)

      P. P. L. Tam and R. S. P. Beddington

    5. Use of Chimeras to Study Gene Function in Mesodermal Tissues During Gastrulation and Early Organogenesis (pages 61–77)

      Rosa S. P. Beddington, Andreas W. Püschel and P. Rashbass

    6. Action of the Brachyury Gene in Mouse Embryogenesis (pages 78–91)

      Bernhard G. Herrmann

    7. Molecular Mechanisms of Pattern Formation in the Vertebrate Hindbrain (pages 92–110)

      M. A. Nieto, L. C. Bradley, P. Hunt, R. Das Gupta, R. Krumlauf and D. G. Wilkinson

    8. Myogenesis in the Mouse (pages 111–131)

      Margaret E. Buckingham, Gary E. Lyons, Marie-Odile Ott and David A. Sassoon

    9. Development of the Skeletal System (pages 132–143)

      R. Balling, C. F. Lau, S. Dietrich, J. Wallin and P. Gruss

    10. Development of the Left-Right Axis (pages 144–161)

      Nigel A. Brown, Afshan McCarthy and Jeong Seo

    11. The Role of sry in Mammalian Sex Determination (pages 162–182)

      Robin Lovell-Badge

    12. Epithelial-Mesenchymal Interactions in Murine Organogenesis (pages 183–198)

      Lauri Saxén and Irma Thesleff

    13. The WNT Family of Cell Signalling Molecules in Postimplantation Development of the Mouse (pages 199–218)

      Andrew P. McMahon, Brian J. Gavin, Brian Parr, Allan Bradley and Jill A. McMahon

    14. The TGF-β-Related DVR Gene Family in Mammalian Development (pages 219–236)

      Karen M. Lyons, C. Michael Jones and Brigid L. M. Hogan

    15. Use of Embryonic Stem Cells to Study Mutations Affecting Postimplantation Development in the Mouse (pages 237–255)

      Elizabeth J. Robertson, Frank L. Conlon, Katrin S. Barth, Frank Costantini and James J. Lee

    16. Genetic Manipulation of the Mouse VIA Gene Targeting in Embryonic Stem Cells (pages 256–276)

      Allan Bradley, Ramiro Ramírez-Solis, Hui Zheng, Paul Hasty and Ann Davis

    17. The Gene Trap Approach in Embryonic Stem Cells: The Potential for Genetic Screens in Mice (pages 277–301)

      Alexandra L. Joyner, Anna Auerbach and William C. Skarnes

    18. Summary (pages 302–303)

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      Index of Contributors (pages 304–305)

    20. You have free access to this content
      Subject Index (pages 306–315)

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