Ciba Foundation Symposium 167 - Polyfunctional Cytokines: IL-6 and LIF

Ciba Foundation Symposium 167 - Polyfunctional Cytokines: IL-6 and LIF

Editor(s): Gregory R. Bock, Joan Marsh, Kate Widdows

Published Online: 28 SEP 2007

Print ISBN: 9780471934394

Online ISBN: 9780470514269

DOI: 10.1002/9780470514269

About this Book

Experts from a variety of areas compare and discuss IL-6 and LIF in order to provide a new understanding of their modes of action, the significance of their polyfunctionalization--why the body chooses to use one molecule to regulate various cell types--and their functional overlap. Covers such topics as actions of IL-6 and LIF on lymphoid populations, on megakaryocyte and platelet production, on bone metabolism, their effects on leukemic cells and much more. Includes contributions from researchers working on a variety of cell types and organ systems along with potential clinical applications regarding these two factors.

Table of contents

    1. You have free access to this content
    2. The Molecular Biology of Interleukin 6 and its Receptor (pages 5–23)

      Tadamitsu Kishimoto, Masahiko Hibi, Masaaki Murakami, Masashi Narazaki, Mikiyoshi Saito and Tetsuya Taga

    3. Regulation of Expression of the Interleukin 6 Gene: Structure and Function of the Transcription Factor NF-IL6 (pages 47–67)

      Shizuo Akira, Hiroshi Isshiki, Toshihiro Nakajima, Shigemi Kinoshita, Yukihiro Nishio, Shunji Natsuka and Tadamitsu Kishimoto

    4. The Action of Interleukin 6 and Leukaemia Inhibitory Factor on Liver Cells (pages 100–124)

      H. Baumann, S. Marinkovic-Pajovic, K.-A. Won, V. E. Jones, S. P. Campos, G. P. Jahreis and K. K. Morella

    5. The Role of Interleukin 6 in Plasmacytomagenesis (pages 188–204)

      Toshio Hirano, Sachiko Suematsu, Taiji Matsusaka, Tadashi Matsuda and Tadamitsu Kishimoto

    6. Interleukin 6 Determination in the Detection of Microbial Invasion of the Amniotic Cavity (pages 205–226)

      Roberto Romero, Waldo Sepulveda, John S. Kenney, Linda E. Archer, Anthony C. Allison and Pravinkumar B. Sehgal

    7. You have free access to this content
    8. You have free access to this content