Ciba Foundation Symposium 176 - The GTPase Superfamily

Copyright © Ciba Foundation 1993

Ciba Foundation Symposium 176 - The GTPase Superfamily

Editor(s): Joan Marsh, Jamie Goode

Published Online: 28 SEP 2007

Print ISBN: 9780471939146

Online ISBN: 9780470514450

DOI: 10.1002/9780470514450

About this Book

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About The Product

Using a multidisciplinary approach, it features contributions and discussions of the latest research from leading scientists working on all aspects of GTPase activity. Covers all known members of the important superfamily of enzymes--the GTPases. Considers numerous key cellular functions and how they are regulated by GTPases. Also describes various regulatory proteins that modulate GTPase activity.

Table of contents

    1. You have free access to this content
      Front Matter (pages i–x)

    2. Introduction (pages 1–5)

      Frank McCormick

    3. Three-Dimensional Structure and Properties of Wild-Type and Mutant H-ras-Encoded p21 (pages 6–27)

      Alfred Wittinghofer, Sybille M. Franken, Axel J. Scheidig, Hans Rensland, Alfred Lautwein, Emil F. Pai and Roger S. Goody

    4. Elongation Factors in Protein Synthesis (pages 28–52)

      B. Kraal, L. Bosch, J. R. Mesters, J. M. de Graaf, L. P. Woudt, E. Vijgenboom, P. W. H. Heinstra, L. A. H. Zeef and C. Boon

    5. RAS Function and Protein Kinase Cascades (pages 53–66)

      Stevan Marcus, Michael Wigler, Hao-Peng Xu, Roymarie Ballester, Makoto Kawamukai and Anthony Polverino

    6. Cell Transformation by ras and Regulation of its Protein Product (pages 67–84)

      Douglas R. Lowy, Maureen R. Johnson, Jeffrey E. Declue, Hui Cen, Ke Zhang, Alex G. Papageorge, William C. Vass, Berthe M. Willumsen, Marcus B. Valentine and A. Thomas Look

    7. Identification of ras Targets using a Genetic Approach (pages 85–95)

      Ulrike Gaul, Henry Chang, Tina Choi, Felix Karim and Gerald M. Rubin

    8. G Proteins in Signal Transduction: The Regulation of Phospholipase C (pages 96–111)

      Paul C. Sternweis and Alan V. Smrcka

    9. The G Protein Cascade of Visual Transduction: Kinetics and Regulation (pages 112–127)

      Marc Chabre, Bruno Antonny, Franz Bruckert And and T. Minh Vuong

    10. Regulators of Small GTPases (pages 128–146)

      Yoshimi Takai, Kozo Kaibuchi, Akira Kikuchi, Takuya Sasaki and Hiromichi Shirataki

    11. A GTPase Cycle in Initiation of Protein Translocation Across the Endoplasmic Reticulum Membrane (pages 147–163)

      Joshua D. Miller and Peter Walter

    12. A Cell-Physiological Description of GE, A GTP-Binding Protein that Mediates Exocytosis (pages 164–184)

      Thomas H. W. Lillie and Bastien D. Gomperts

    13. Dynamin, a GTPase Involved in the Initial Stages of Endocytosis (pages 185–197)

      Richard B. Vallee, Jonathan S. Herskovits, John G. Aghajanian, Christopher C. Burgess and Howard S. Shpetner

    14. The VPS1 Protein is a Dynamin-Like GTPase Required for Sorting Proteins to the Yeast Vacuole (pages 198–217)

      Kirk Ekena, Carol A. Vater, Christopher K. Raymond and Tom H. Stevens

    15. The Cycle of SEC4 Function in Vesicular Transport (pages 218–232)

      Peter Novick, Patrick Brennwald, Nancy C. Walworth, Alisa K. Kabcenell, Michelle Garrett, Mary Moya, Denise Roberts, Heike Müller, Brinda Govindan and Robert Bowser

    16. Mx Proteins: Gtpases Involved in the Interferon-Induced Antiviral State (pages 233–247)

      Jovan Pavlovic, Anja Schröder, Antje Blank, Fernando Pitossi and Peter Staeheli

    17. Should the Tubulins be Members of the GTPase Superfamily? (pages 248–277)

      Roy G. Burns, Kevin W. Farrell and Christopher D. Surridge

    18. Summing-Up (pages 278–279)

      Frank McCormick

    19. You have free access to this content
      Index of Contributors (pages 280–281)

    20. You have free access to this content
      Subject Index (pages 282–289)

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