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Ciba Foundation Symposium 204 - The Molecular Basis of Cellular Defence Mechanisms

Copyright © 1997 John Wiley & Sons Ltd.

Ciba Foundation Symposium 204 - The Molecular Basis of Cellular Defence Mechanisms

Editor(s): Gregory R. Bock, Jamie A. Goode

Published Online: 28 SEP 2007

Print ISBN: 9780471965671

Online ISBN: 9780470515280

DOI: 10.1002/9780470515280

About this Book

Product Information

About The Product

The field of lymphokine research has grown in parallel to the exciting developments around the two sets of cells which defend the body. While lymphokines are the "property" of immunologists, the molecular regulators of hemopoiesis (CSFs) belong to the hematologists. This book offers the rare opportunity to examine these separate fields of expertise together.

Table of contents

    1. You have free access to this content
      Front Matter (pages i–x)

    2. Chairman's Introduction (pages 1–2)

      Sir Gustav Nossal

    3. How Do Stem Cells Decide What To Do? (pages 3–18)

      Michael A. Cross, Clare M. Heyworth and T. Michael Dexter

    4. The Structural Basis of the Biological Actions of the GM-CSF Receptor (pages 19–39)

      Nicos A. Nicola, Alison Smith, Lorraine Robb, Donald Metcalf and C. Glenn Begley

    5. The Molecular Control of Granulocytes and Macrophages (pages 40–59)

      Donald Metcalf

    6. CSF-Deficient Mice — What Have They Taught Us? (pages 60–77)

      Graham J. Lieschke

    7. Clinical Benefits of Improving Host Defences with rHuG-CSF (pages 78–93)

      George Morstyn, Mary Ann Foote and Steve Nelson

    8. T Cell Receptor Biochemistry, Repertoire Selection and General Features of TCR and Ig Structure (pages 94–104)

      M. M. Davis, D. S. Lyons, J. D. Altman, M. McHeyzer-Williams, J. Hampl, J. J. Boniface and Y. Chien

    9. Immunology and Immunity Studied with Viruses (pages 105–129)

      Rolf M. Zinkernagel

    10. Dendritic Cells and T Lymphocytes: Developmental and Functional Interactions (pages 130–147)

      Ken Shortman, Li Wu, Gabriele Süss, Vadim Kronin, Ken Winkel, Dolores Saunders and David Vremec

    11. Differentiation and Functions of T Cell Subsets (pages 148–158)

      Tim R. Mosmann, Li Li, Hans Hengartner, David Kagi, Wayne Fu and Subash Sad

    12. T Cell Tolerance and Autoimmunity (pages 159–171)

      J. F. A. P. Miller, W. R. Heath, J. Allison, G. Morahan, M. Hoffmann, C. Kurts and H. Kosaka

    13. Control of the Sizes and Contents of Precursor B Cell Repertoires in Bone Marrow (pages 172–189)

      Fritz Melchers

    14. Glimpses into the Balance Between Immunity and Self-Tolerance (pages 190–207)

      Christopher C. Goodnow

    15. Interleukin 4: Signalling Mechanisms and Control of T Cell Differentiation (pages 208–219)

      William E. Paul

    16. B Lymphocyte Physiology: The Beginning and the End (pages 220–236)

      G. J. V. Nossal

    17. Summing-Up (pages 237–238)

      Sir Gustav Nossal

    18. You have free access to this content
      Index of Contributers (pages 239–240)

    19. You have free access to this content
      Subject Index (pages 241–250)

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