Ciba Foundation Symposium 212 - Plasminogen-Related Growth Factors

Copyright © Ciba Foundation 1997

Ciba Foundation Symposium 212 - Plasminogen-Related Growth Factors

Editor(s): Gregory R. Bock, Jamie A. Goode

Published Online: 28 SEP 2007

Print ISBN: 9780471974567

Online ISBN: 9780470515457

DOI: 10.1002/9780470515457

About this Book

Product Information

About The Product

A timely volume dealing with the evolutionary and structural links between the clotting and fibrinolytic proteins and plasminogen-related growth factors. The role of individual domains for enzymatic proteins and plasminogen-related growth factors is also comprehensively examined.

Table of contents

    1. You have free access to this content
      Front Matter (pages i–viii)

    2. Chairman's Introduction (pages 1–3)

      Ermanno Gherardi

    3. Evolution of Vertebrate Fibrin Formation and the Process of its Dissolution (pages 4–23)

      Russell F. Doolittle, Glen Spraggon and Stephen J. Everse

    4. Evolution of Plasminogen-Related Growth Factors (HGF/SF and HGF1/MSP) (pages 24–45)

      Ermanno Gherardi, Ramon Gonzalez Manzano, Amanda Cottage, Kelvin Hawker and Samuel Aparicio

    5. The Kringle Domains of Human Plasminogen (pages 46–65)

      Francis J. Castellino and Stephen G. McCance

    6. Structure and Function of Microplasminogen: Reconstitution of Microplasminogen and Microplasmin from Isolated Fragments (pages 66–83)

      Teresa de los Santos, Jieyi Wang and Edward Reich

    7. Domain Structure of Hepatocyte Growth Factor/Scatter Factor (HGF/SF) (pages 84–104)

      Ermanno Gherardi, Guido Hartmann, Jonathan Hepple, Dimitri Chirgadze, N. Srinivasan and Tom Blundell

    8. Plasminogen/Plasminogen Activator and Growth Factor Activation (pages 105–118)

      D. B. Rifkin, P. E. Gleizes, J. Harpel, I. Nunes, J. Munger, R. Mazzieri and I. Noguera

    9. Met–HGF/SF: Tumorigenesis, Invasion and Metastasis (pages 119–132)

      G. F. Vande Woude, M. Jeffers, J. Cortner, G. Alvord, I. Tsarfaty and J. Resau

    10. Scatter Factor Receptors are Key Players in a Unique Multistep Program Leading to Invasive Growth (pages 133–154)

      Alberto Bardelli and Paolo M. Comoglio

    11. Competence for Neural Induction: HGF/SF, HGFl/MSP and the c-Met Receptor (pages 155–168)

      Andrea C. E. Streit and Claudio D. Stern

    12. The Functions of HGF/SF and its Receptor, the c-Met Tyrosine Kinase, in Mammalian Development (pages 169–182)

      Carmen Birchmeier, Friedhelm Bladt and Tomoichiro Yamaai

    13. Biological Aspects of Macrophage-Stimulating Protein (MSP) and its Receptor (pages 183–197)

      Edward J. Leonard

    14. HGF: Its Organotrophic Role and Therapeutic Potential (pages 198–214)

      Kunio Matsumoto and Toshikazu Nakamura

    15. HGF/SF in Angiogenesis (pages 215–229)

      Eliot M. Rosen, Katrin Lamszus, John Laterra, Peter J. Polverini, Jeffrey S. Rubin and Itzhak D. Goldberg

    16. Role of HGF/SF and c-Met in Morphogenesis and Metastasis of Epithelial Cells (pages 230–251)

      Walter Birchmeier, Volker Brinkmann, Catherin Niemann, Silke Meiners, Silvana DiCesare, Helga Naundorf and Martin Sachs

    17. Chairman's Summing-Up (pages 252–253)

      Ermanno Gherardi

    18. You have free access to this content
      Index of Contributors (pages 254–255)

    19. You have free access to this content
      Subject Index (pages 256–260)

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