Biofilm Eradication and Prevention: A Pharmaceutical Approach to Medical Device Infections

Biofilm Eradication and Prevention: A Pharmaceutical Approach to Medical Device Infections

Author(s): Tamilvanan Shunmugaperumal

Published Online: 29 JUN 2010

Print ISBN: 9780470479964

Online ISBN: 9780470640463

DOI: 10.1002/9780470640463

About this Book

Biofilm Eradication and Preventions presents the basics of biofilm formation on medical devices, diseases related to this formation, and approaches pharmaceutical researchers need to take to limit this problem. Split into three parts, the first deals with the development and characterization of biofilm on the surfaces of implanted or inserted medical devices. Questions as to why biofilms form over medical device surfaces and what triggers biofilm formation are addressed. In the second section, the author discusses biofilm-mediated chronic infections occurred in various organs (eyes, mouth, wounds) and pharmaceutical and drug delivery knowledge gained from research in these area. The third part explores pharmaceutical approaches like lipid-and polymer-based drug delivery carriers for eradicating biofilm on device-related infections. In addition, this section also explores the topic of novel small molecule (like iron and its complexes/metal chelators) and a quorum-sensing inhibitors to control medical biofilm formation.

Table of contents

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    1. You have free access to this content
  1. Part I: Development and Characterization of Biofilms

  2. Part II: Biofilm - Related Infections in Various Human Organs (Nondevice - Related Chronic Infections)

  3. Part III: Drug Delivery Carriers to Eradicate Biofilm formation on Medical Devices

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