Solid State Characterization of Pharmaceuticals

Solid State Characterization of Pharmaceuticals

Editor(s): Richard A. Storey, Ingvar Ymén

Published Online: 31 MAR 2011 08:31PM EST

Print ISBN: 9781405134941

Online ISBN: 9780470656792

DOI: 10.1002/9780470656792

About this Book

The field of solid state characterization is central to the pharmaceutical industry, as drug products are, in an overwhelming number of cases, produced as solid materials. Selection of the optimum solid form is a critical aspect of the development of pharmaceutical compounds, due to their ability to exist in more than one form or crystal structure (polymorphism). These polymorphs exhibit different physical properties which can affect their biopharmaceutical properties.

This book provides an up-to-date review of the current techniques used to characterize pharmaceutical solids. Ensuring balanced, practical coverage with industrial relevance, it covers a range of key applications in the field. 

The following topics are included:    

  • Physical properties and processes
  • Thermodynamics
  • Intellectual  guidance
  • X-ray diffraction
  • Spectroscopy Microscopy
  • Particle sizing
  • Mechanical properties
  • Vapour sorption
  • Thermal analysis & Calorimetry
  • Polymorph prediction
  • Form selection

Table of contents

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