Patai's Chemistry of Functional Groups

Patai's Chemistry of Functional Groups

Online ISBN: 9780470682531

DOI: 10.1002/9780470682531

About this Book

The most comprehensive work in functional groups now available as a fully searchable major online reference resource with additional functionality and search facilities.

Now available for the first time as a searchable, fully updating e-MRW, the landmark book series, The Chemistry of Functional Groups, founded by Saul Patai in 1964.

Patai covers all aspects of the chemistry of functional groups – an essential tool for the organic chemist – including physical organic chemistry, analytical chemistry and techniques, reaction mechanisms, chapters on synthetic pathways, reactions and strategies as well as applications in drug discovery, pharmaceuticals, biochemistry and molecular biology.

This is the most complete, comprehensive work in functional group chemistry. The uniqueness of its content is two-fold, its review style giving additional understanding beyond reactions and data and the breadth of the coverage, specifically in the areas of physical organic chemistry and analytical techniques.

A key working reference for the advanced postgraduate, senior researcher or organic chemist in industry, but also an information resource for more junior researchers and students.

Volumes from 1996 onwards are accessible through one site, with features such as full-text alphanumerical searching, browse by topic and cross-referencing. Older volumes from 1964 to 1995 are available as a backfile, making classic volumes available online for the first time, to give complete access to the whole of Patai.

PATAI’S Chemistry of Functional Groups takes the successful, long-standing and highly regarded book series “The Chemistry of Functional Groups”, founded by the late Saul Patai in 1964, fully into the online environment. Launched in December 2009, it includes the content of all volumes published since 1996. New volumes are first published online, and subsequently in print format.

In addition, the older, historic Patai volumes (from 1964 to 1995) are available as a book series backfile. The backfile contains over 100 volumes of the series with a combined extent of 58,500 pages.

PATAI’S Chemistry of Functional Groups covers, in each volume, all key aspects of the chemistry – i.e. physical, analytical, synthetic, applications areas (see more details below) - of one of the important functional groups in organic chemistry. The emphasis is on the functional group treated, and on the effect which it exerts on the chemical and physical properties of the molecule, firstly in the immediate vicinity of the functional group, and secondly, on the behaviour of the molecule as a whole.

The treatment of the various functional groups is aimed primarily at a research level audience, and focuses on information that is not already readily available in other major secondary or tertiary sources, such as Chemical Reviews, Quarterly Reviews, Organic Reactions, various ‘Advances’ and ‘Progress’ series as well as textbooks. Patai concentrates on the most important recent developments in functional group chemistry that have not been adequately covered by reviewers or other secondary sources, so provides an ideal reference for advanced postgraduates, researchers and academics in all branches of organic chemistry. It is also used by other researchers in related areas in the molecular sciences i.e. by biochemists and pharmaceutical and medicinal chemists.

Each volume includes detailed information on the following topics:

  • General, theoretical and computational aspects of the functional group, for example, quantum chemical treatment, structural and conformational chemistry, and thermochemistry.

  • Characterization and characteristics of functional groups with chapters covering both qualitative and quantitative methods of determination, such as UV, IR, NMR, ESR, PES, RD, CD and mass spectrometry. It also covers the basicity, acidity or the complex forming ability of the group.

  • Chapters dealing with both the formation of the functional group and the reactions, transformations and rearrangements which the functional group can undergo. This can cover synthesis and reaction mechanisms as diverse as photochemistry, radiation chemistry, biochemical formation or classic synthesis and catalysis.

  • Chapters on the biological aspects of the functional group in both biochemistry and molecular biology, as well as its applications in medicinal chemistry, drug development and drug discovery.

  • Data and reviews on the important industrial applications such as polymers, materials and nano-materials.

  • Special topics: Depending on the nature of each functional group treated, these special topics may include short reviews on related functional groups on which no separate volume is planned.

 To find out more about the Patai series in both print and online including the online book series as well as the electronic reference work, go to you can download a brochure and access additional information about the series.


All volumes published from 1964 to 1995 are published as a backfile. PATAI’S Chemistry of Functional Groups Backfile is available as an OnlineBooksseries, view here.

Patai-Rappoport Lecture at ESOC 2015

Prof. Ilan Marek, Editor-in-Chief of the Patai series, introduces the first Patai-Rappoport Lecture at ESOC 2015.

Prof. Ilan Marek

Awarded to Peter Chen, ETH Zurich, for advancing the chemistry of functional groups.

Peter Chen

ePatai now features The Smart Article

Introducing new and enhanced article tools for chemistry content. Watch 'The Smart Article in Action' and find out how these new features can aid your research. Simply click here to watch the short video.

The following articles are excellent examples of the new functionality within ePatai, and are free to access:

Synthesis of Anilines

Structural Organozinc Chemistry

Cubanes, Fenestranes, Ladderanes, Prismanes, Staffanes and Other Oligocyclobutanoids

Find out more about the new features here

The Smart Article