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Topley and Wilson's Microbiology and Microbial Infections

Topley and Wilson's Microbiology and Microbial Infections

Online ISBN: 9780470688618

DOI: 10.1002/9780470688618

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  1. Bacteriology
    1. General Basic Characteristics
      1. The Bacteria: Historical Introduction
      2. Taxonomy and Nomenclature of Bacteria
      3. Bacterial Growth and Metabolism
      4. Bacterial Genetics
      5. Bacteriocins and bacteriophages
      6. Molecular Basis of Bacterial Adaptation to a Pathogenic Lifestyle
    2. General Ecosystems
      1. Airborne Bacteria
      2. Bacteriology of Soils and Plants
      3. Bacteriology of Water
      4. Bacteriology of Milk and Milk Products
      5. Bacteriology of Foods, Excluding Dairy Products
      6. Human Microbiota
    3. General Epidemiology, Transmission, and Therapy
      1. Epidemiology of Infectious Diseases
      2. Theory of Infectious Disease Transmission and Control
      3. Emergence and Resurgence of Bacterial Infectious Diseases
      4. Healthcare–Associated Infections
      5. Microbial susceptibility and resistance to chemical and physical agents
      6. Antibacterial Therapy
    4. Organ and System Infections
      1. Bloodstream Infection and Endocarditis
      2. Bacterial Meningitis
      3. Other CNS Bacterial Infections
      4. Bacterial Infections of the Eye
      5. Bacterial Infections of the Upper Respiratory Tract
      6. Bacterial Infections of the Lower Respiratory Tract
      7. Bacterial Infections of the Genital Tract
      8. Bacterial Infections of the Urinary Tract
      9. Bacterial Infections of Bones and Joints
    5. Laboratory Aspects
      1. Conventional Laboratory Diagnosis of Infection
      2. Molecular Laboratory Diagnosis of Infection
      3. Bacterial Immunoserology
      4. Biological Safety for the Clinical Laboratory
    6. Organisms and Their Biology
      1. Staphylococcus
      2. Streptococcus and Lactobacillus
      3. Enterococcus
      4. Gram-Positive Anaerobic Cocci
      5. Bacillus Anthracis, Bacillus Cereus, and Other Aerobic Endospore-Forming Bacteria
      6. Listeria
      7. Erysipelothrix
      8. Corynebacteria and Rare Coryneforms
      9. Tropheryma
      10. Actinomyces and Related Genera
      11. Bifidobacterium, Eubacterium, and Propionibacterium
      12. Clostridium botulinum and Clostridium tetani
      13. Clostridium perfringens, Clostridium difficile, and Other Clostridium Species
      14. Nocardia and other Aerobic Actinomycetes
      15. Mycobacterium tuberculosis Complex, Mycobacterium leprae, and Other Slow-Growing Mycobacteria
      16. Rapidly Growing Mycobacteria
      17. Neisseria
      18. Acinetobacter and Moraxella
      19. Veillonella and Other Anaerobic Gram-Negative Cocci
      20. The Enterobacteriaceae: General Characteristics
      21. Escherichia
      22. Shigella
      23. Salmonella
      24. Proteus, Morganella, and Providencia
      25. Yersinia
      26. Citrobacter, Enterobacter, Klebsiella, Plesiomonas, Serratia, and Other Members of the Enterobacteriaceae
      27. Vibrio
      28. Aeromonas
      29. Campylobacter and Arcobacter
      30. Helicobacter
      31. Pseudomonas
      32. Burkholderia spp. and Related Genera
      33. Pasteurella, Mannheimia, Actinobacillus, Eikenella, Kingella, Capnocytophaga, and Other Miscellaneous Gram-Negative Rods
      34. Haemophilus
      35. Brucella
      36. Francisella
      37. Legionella
      38. Bordetella
      39. Borrelia
      40. Treponema
      41. Leptospira
      42. Bartonella and Afipia
      43. Spirillum minus and Streptobacillus moniliformis
      44. Bacteroides, Prevotella, and Porphyromonas
      45. Fusobacterium and Leptotrichia
      46. Mycoplasma
      47. Chlamydia
      48. Rickettsia and Orienta
      49. Ehrlichia and Anaplasma
      50. Coxiella burnetii
  2. Immunology
    1. Introduction
      1. Introduction
      2. History
    2. Innate Immunity and Infection
      1. Phagocytes Part 1: Macrophages
      2. Phagocytes Part 2: Neutrophils
      3. Basophils and Eosinophils
      4. Natural Killer Cells
      5. Pattern Recognition
      6. Apoptosis
      7. Complement
      8. Antimicrobial Peptides: Defensins and Cathelicidins
      9. Lipid Mediators: Leukotrienes, Prostanoids and Other Lipids
      10. The Acute Phase Response
    3. Soluble Mediators
      1. Chemokines
      2. Type I Interferons and Receptors
      3. Cytokines
    4. Acquired Immunity
      1. Antibodies and B Lymphocytes
      2. The B-Cell Antigen Receptor
      3. Monoclonal Antibody Therapy
      4. Processing and Presentation of Antigen by the Class II Histocompatibility System
      5. CD4+ T Lymphocytes
      6. MHC Class I Antigen Processing System
      7. The Role of CD8 T Cells in the Control of Infectious Disease and Malignancies
      8. Unconventional T Cells
      9. T-Cell Receptors
      10. Lymphocyte-Mediated Cytotoxicity
      11. Immunological Memory
      12. Lymphocyte Homing
      13. The Mucosal Immune Response
      14. Superantigens
      15. Immunogenetics
    5. Infection and Immunity
      1. Viral Interference with the Host Immune Response
      2. Evasion of Immune Responses by Bacteria
      3. Parasite Evasion
    6. Immunopathology and Immunodeficiency
      1. Shock/Sepsis
      2. DTH-Associated Pathology
      3. Airway Hypersensitivity
      4. Autoimmunity
      5. The Immunocompromised Host
      6. Acquired immunodeficiencies
    7. Vaccines
      1. New Approaches to Vaccine Delivery
      2. New Vaccine Technologies
      3. Peptide Vaccines
      4. Live Vaccine Carriers
      5. Naked DNA Vaccines
      6. Adjuvants and Subunit Vaccines
      7. Mathematical Models of Vaccination
  3. Medical Mycology
    1. Background and Basic Information
      1. Historical Introduction: Evolution of Knowledge of the Fungi and Mycoses from Hippocrates to the Twenty-First Century
      2. Kingdom Fungi: Fungal Phylogeny and Systematics
      3. Fungal Structure and Morphology
      4. Laboratory Diagnosis
      5. Mycoserology and Molecular Diagnosis
      6. Histopathological Diagnosis of Mycotic Diseases
    2. Therapeutic Agents and Vaccines
      1. Antifungal Agents and Antifungal Susceptibility Testing
      2. Principles of Antifungal Therapy
      3. Resistance to Antifungal Agents
      4. Management of Superficial Infections
    3. Superficial and Ocular Fungal Infections
      1. White Piedra, Black Piedra, and Tinea Nigra
      2. Superficial Diseases Caused by Malassezia Species
      3. The Dermatophytes
      4. Dermatomycotic Molds
      5. Superficial Candidiasis
      6. Oculomycosis
    4. Subcutaneous Mycoses
      1. Subcutaneous Zygomycosis
      2. Chromoblastomycosis
      3. Sporotrichosis
      4. Eumycetomas
      5. Protothecosis
      6. Pythiosis
      7. Lobomycosis
      8. Rhinosporidiosis
    5. Systemic Mycoses Due to Dimorphic Fungi
      1. Blastomycosis
      2. Coccidioidomycosis
      3. Histoplasmosis
      4. Paracoccidioidomycosis
      5. Penicilliosis
    6. Systemic Mycoses Caused by Opportunistic Fungi
      1. Candidiasis
      2. Serious Infections Caused by Uncommon Yeasts
      3. Cryptococcosis
      4. Systemic Zygomycosis
      5. Aspergillosis
      6. Deep Phaeohyphomycosis
      7. Deep Hyalohyphomycosis
      8. Pneumocystis pneumonia
    7. Unusual Disease Presentations by Fungi
      1. Adiaspiromycosis and other Infections Caused by Emmonsia Species
  4. Parasitology
    1. General Parasitology
      1. History of Human Parasitology
      2. World-Wide Importance of Parasites
      3. Epidemiology of Parasitic Infections
      4. Immunology and Immunopathology of Human Parasitic Infections
      5. Control of Parasites, Parasitic Infections, and Parasitic Diseases
      6. Diagnosis of Parasitic Infections
    2. Protozoa
      1. Cellular Organization of Parasitic Protozoa
      2. Classification and Introduction to the Parasitic Protozoa
      3. Amebiasis: Entamoeba Histolytica Infections
      4. Other Intestinal Amebae
      5. Opportunistic Amebae
      6. Giardiasis
      7. Trichomonas Infections
      8. Dientamoeba fragilis and Other Intestinal Flagellates
      9. Balantidium coli
      10. Old World Leishmaniasis
      11. New World Leishmaniasis
      12. African Trypanosomiasis
      13. New World Trypanosomiasis
      14. Intestinal Coccidia: Cryptosporidiosis, Isosporiasis, Cyclosporiasis
      15. Toxoplasmosis
      16. Babesiosis of humans
      17. Babesiosis of Humans
      18. Malaria
      19. Microsporidiosis
      20. Blastocystis hominis
    3. Helminths
      1. Nature and Classification of Parasitic Helminths
      2. Schistosomes: General
      3. Schistosomes: African
      4. Schistosomes: Asian
      5. Lung and liver flukes
      6. Intestinal Tapeworms
      7. Larval Cestodes
      8. Gastrointestinal Nematodes Ascaris, Hookworm, Trichuris, and Enterobius
      9. Strongyloides and Capillaria
      10. Toxocara
      11. Trichinella
      12. Lymphatic Filariasis
      13. Onchocerciasis
      14. Angiostrongylus (Parastrongylus) and Less Common Nematodes
      15. Dracunculiasis
  5. Virology
    1. General Characteristics of Viruses
      1. A Short History of Research on Viruses
      2. The Origin and Evolution of Viruses
      3. The Nature and Classification of Viruses
      4. The Classification of Vertebrate Viruses
      5. The Morphology and Structure of Viruses
      6. Propagation and Identification of Viruses
      7. The Replication of Viruses
      8. Negative-Strand RNA Virus Replication
      9. Positive-Strand RNA Virus Replication in Vertebrate Hosts
      10. DNA Virus Replication
      11. Genetics of Vertebrate Viruses
      12. Virus–Host Cell Interactions
      13. Pathogenesis of Viral Infections
      14. The Immune Response to Viral Infections
      15. The Role of Cytokines in Viral Infections
      16. Viral Evasion of the Host Immune Response
      17. Viral Oncogenicity
      18. The Epidemiology of Viral Infections
      19. The Order Mononegavirales
      20. The Order Nidovirales
    2. Specific Viruses and Viral Infections
      1. Parvoviruses
      2. Adenoviruses
      3. Papillomaviruses
      4. Polyomaviruses
      5. Herpesviruses: General Properties
      6. Alphaherpesviruses: Herpes Simplex and Varicella-Zoster
      7. Betaherpesviruses: Cytomegalovirus, Human Herpesviruses 6 and 7
      8. Human Herpesvirus 8
      9. Gammaherpesviruses: Epstein-Barr Virus
      10. Poxviruses
      11. Poxvirus Replication
      12. Orthomyxoviruses: Influenza
      13. General Properties of the Paramyxoviruses
      14. Morbilliviruses: Measles Virus
      15. Rubulavirus: Mumps Virus
      16. Respiroviruses: Parainfluenza Virus
      17. Pneumovirus and Metapneumovirus: Respiratory Syncytial Virus and Human Metapneumovirus
      18. Paramyxoviruses of Animals
      19. Coronaviruses, Toroviruses, and Arteriviruses
      20. Picornaviruses
      21. Human Enteric RNA Viruses: Astroviruses
      22. Human Enteric RNA Viruses: Noroviruses and Sapoviruses
      23. Reoviruses, Orbiviruses, and Coltiviruses
      24. Rotaviruses
      25. Rubella
      26. Flaviviruses
      27. Togaviruses
      28. Bunyaviridae
      29. Arenaviruses
      30. Filoviruses
      31. Rhabdoviruses: Rabies
      32. Borna Disease Virus
      33. Hepatitis A and E
      34. Hepatitis C Virus
      35. Hepatitis B
      36. Hepatitis Delta Virus
      37. TT Virus and Other Anelloviruses
      38. Retroviruses and Associated Diseases in Humans
      39. Foamy Viruses
      40. Human Immunodeficiency Virus
      41. Prions of Humans and Animals
    3. Syndromes Caused by a Range of Viruses
      1. Infections of the Central Nervous System
      2. Viral Infections of the Fetus and Neonate, other than Rubella
      3. Virus Infections in Immunocompromised Patients
    4. Principles of Diagnosis and Control
      1. Safety in the Virology Laboratory
      2. The Laboratory Diagnosis of Viral Infections
      3. Immunoprophylaxis of Viral Diseases
      4. Viral Vectors for Gene Therapy
      5. Antiviral Chemotherapy
      6. The Emergence and Re-Emergence of Viral Diseases

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