Immune Dysfunction and Immunotherapy in Heart Disease

Immune Dysfunction and Immunotherapy in Heart Disease

Editor(s): Ronald Ross Watson, Douglas F. Larson

Published Online: 15 APR 2008

Print ISBN: 9781405155687

Online ISBN: 9780470692325

DOI: 10.1002/9780470692325

About this Book

Current heart failure therapeutics affects symptoms without appreciably reducing the mortality rate of 50% in five years -- suggesting a failure in treating the underlying mechanism. This book proposes a new mechanism for heart failure; immune mediated cardiac remodelling for cardiac dysfunction.

The outstanding editor team of two internationally recognized immunologists -- Ronald Watson, who has studied heart disease in immune dysfunction for a decade and has a patent for an immunotherapy of heart disease by immune regulation, and Douglas Larson, whose experience in cardiac transplantation immunology has provided the foundation for research into novel therapeutics for heart failure and hypertension - makes Immune Dysfunction and Immunotherapy in Heart Disease the definitive reference to the state of the science in this area.

The four parts of the book address:


  • Immune Dysfunction Leading to Heart Disease: Induction by Physiological Changes
  • Immune Dysfunction Promoting CVD: Induction by Transplantation Drugs
  • Immune Dysfunction Leading to Heart Dysfunction: Induction or Prevention by Cardiotherapeutic Drugs
  • Immune Dysfunction Leading to Heart Disease: Induction by Pathogens

Both researchers and practitioners will find this authoritative volume an excellent source of information on novel immune targeted therapeutics.

Table of contents

    1. You have free access to this content
  1. Part I: Immune Dysfunction Leading to Heart Disease: Induction by Physiological Changes

    1. Chapter 2

      Immune Mechanisms in Pediatric Cardiovascular Disease (pages 6–16)

      Wendy A. Luce, Mandar S. Joshi, Timothy M. Hoffman, Timothy F. Feltes and John Anthony Bauer

  2. Part II: Immune Dysfunction Promoting CVD: Induction by Transplantation Drugs

    1. Chapter 10

      Immunomodulating Therapy in Chronic Heart Failure (pages 97–108)

      Lars Gullestad, Jan Kristian Damås, Arne Yndestad and Pål Aukrust

  3. Part III: Immune Dysfunction Leading to Heart Dysfunction: Induction or Prevention by Cardiotherapeutic Drugs

  4. Part IV: Immune Dysfunction Leading to Heart Disease: Induction by Pathogens

    1. Chapter 22

      Anti-Inflammatory Immune Therapy in Heart Disease (pages 217–226)

      David Chen, Christian Assad‒Kottner, Francisco J. Cordova, Carlos Orrego and Guillermo Torre‒Amione

    1. You have free access to this content

SEARCH