Ciba Foundation Symposium 68 - Enzyme Defects and Immune Dysfunction

Copyright © 1979 Ciba Foundation

Ciba Foundation Symposium 68 - Enzyme Defects and Immune Dysfunction

Editor(s): Katherine Elliott, Julie Whelan

Published Online: 30 MAY 2008

Print ISBN: 9780444900883

Online ISBN: 9780470720516

DOI: 10.1002/9780470720516

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Table of contents

    1. You have free access to this content
      Frontmatter (pages i–ix)

    2. Chapter 1

      Chairman's Introduction (pages 1–2)

      D. W. Martin

    3. Chapter 2

      Adenosine Deaminase and Purine Nucleoside Phosphorylase Deficiency: How They Were Discovered and What They May Mean (pages 3–18)

      Eloise R. Giblett

    4. Chapter 3

      Buridan's Ass: One Man's View of the Immune System (pages 19–34)

      Jan Klein

    5. Chapter 4

      Clinical Delineation of Adenosine Deaminase Deficiency (pages 35–54)

      Rochelle Hirschhorn

    6. Chapter 5

      Immunological Aberrations in Purine Nucleoside Phosphorylase Deficiencies (pages 55–75)

      Arthur J. Ammann

    7. Chapter 6

      Immunodeficiency Due to Transcobalamin II Deficiency (pages 77–99)

      W. H. Hitzig, Marijke Fràter-Schröder and R. Seger

    8. Chapter 7

      Nucleotide Metabolism in Cultured T Cells and in Cells of Patients Deficient in Adenosine Deaminase and Purine Nucleoside Phosphorylase (pages 101–114)

      Amos Cohen, Lorraine J. Gudas, Buddy Ullman and David W. Martin

    9. Chapter 8

      Deoxyribonucleoside Toxicity in Adenosine Deaminase and Purine Nucleoside Phosphorylase Deficiency: Implications for the Development of New Immunosuppressive Agents (pages 115–133)

      Dennis A. Carson and Jonathan Kaye

    10. Chapter 9

      Ecto 5′-Nucleotidase Deficiency in Primary Hypogammaglobulinaemia (pages 135–164)

      A. D. B. Webster, M. Rowe, S. M. Johnson, G. L. Asherson and A. Harkness

    11. Chapter 10

      Allosteric Regulation of Calf Thymusribonucleotide Reductase (pages 165–175)

      S. Eriksson and L. Thelander

    12. Chapter 11

      Adenosine Deaminase: Characteristics of the Normal and Mutant Forms of the Human Enzyme (pages 177–191)

      Peter E. Daddona and William N. Kelley

    13. Chapter 12

      Purine Nucleoside Phosphorylase: The Normal Enzyme and Structural Alterations in Immunodeficiency Disease (pages 193–205)

      Irving H. Fox, Catherine M. Andres, Janice Kaminska and Robert L. Wortmann

    14. Chapter 13

      Purine Nucleoside Phosphorylase: Immunodetection and Characterization of the Human Enzyme (pages 207–211)

      Gabrielle H. Reem

    15. Chapter 14

      Enzyme Replacement and Other Biochemical Approaches to the Therapy of Adenosine Deaminase Deficiency (pages 213–230)

      Stephen H. Polmar

    16. Chapter 15

      An Approach to the Restoration of T Cell Function in a Purine Nucleoside Phosphorylase Deficient Patient (pages 231–253)

      B. J. M. Zegers, J. W. Stoop, G. E. J. Staal and S. K. Wadman

    17. Chapter 16

      Purine Metabolism in Adenosine Deaminase Deficiency (pages 255–279)

      H. Anne Simmonds, A. Sahota, C. F. Potter, D. Perrett, K. Hugh-Jones and J. G. Watson

    18. You have free access to this content
      Index of Contributors (pages 281–282)

    19. You have free access to this content
      Subject index (pages 283–289)

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