Ciba Foundation Symposium 74 - Drug Concentrations in Neuropsychiatry

Copyright © 1980 Ciba Foundation

Ciba Foundation Symposium 74 - Drug Concentrations in Neuropsychiatry

Editor(s): Ruth Porter, John Rivers, Julie Whelan

Published Online: 30 MAY 2008

Print ISBN: 9780444901378

Online ISBN: 9780470720578

DOI: 10.1002/9780470720578

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Table of contents

    1. You have free access to this content
      Frontmatter (pages i–viii)

    2. Chapter 1

      Introduction: The Rational Use of Plasma Drug Levels in Clinical Medicine (pages 1–12)

      Louis Lasagna

    3. Chapter 2

      Principles of Pharmacokinetics (pages 13–33)

      Geoffrey T. Tucker

    4. Chapter 3

      Methodological Pitfalls: The Influence of Experimental Design on Results (pages 35–49)

      Stephen H. Curry

    5. Chapter 4

      Interpretation of Drug Levels: Relevance of Plasma Protein Binding (pages 51–68)

      Emilio Perucca and Alan Richens

    6. Chapter 5

      Quality Control of Drug Assays (pages 69–79)

      Alan Richens

    7. Chapter 6

      Lithium Concentrations and Clinical Responses (pages 81–98)

      John L. Crammer, A.C. Elithorn and R. Lennox

    8. Chapter 7

      Blood Levels of Flupenthixol in Patients with Acute and Chronic Schizophrenia (pages 99–114)

      Eve C. Johnstone, Rachel C. Bourne, P. Mary Cotes, T.J. Crow, I.N. Ferrier, F. Owen and J.D. Robinson

    9. Chapter 8

      Clinical Significance of Monitoring Plasma Levels of Psychotropic Drugs (pages 115–139)

      Paolo Lucio Morselli and Edouard Zarifian

    10. Chapter 9

      Benzodiazepines: Some Aspects of Their Clinical Pharmacology (pages 141–155)

      Richard I. Shader and David J. Greenblatt

    11. Chapter 10

      Adrenergic and Serotonergic Mechanisms in Depression and Their Response to Amitriptyline (pages 157–166)

      Alec Coppen and Keith Wood

    12. Chapter 11

      The Role of Plasma Level Monitoring of Tricyclic Antidepressant Drugs as an Aid to Treatment (pages 167–197)

      Robin Braithwaite

    13. Chapter 12

      Clinical Application of the Monitoring of Anticonvulsant Drug Levels (pages 199–214)

      E.H. Reynolds

    14. Chapter 13

      The Logistics of Drug Monitoring (pages 215–224)

      Roy Goulding

    15. Chapter 14

      Alternative Approaches (pages 225–252)

      Malcolm Lader

    16. Chapter 15

      Concluding Remarks (pages 253–255)

      Louis Lasagna

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      Appendix (pages 257–258)

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      Index of Contributors (page 259)

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      Subject Index (pages 259–261)

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