Superbases for Organic Synthesis: Guanidines, Amidines, Phosphazenes and Related Organocatalysts

Superbases for Organic Synthesis: Guanidines, Amidines, Phosphazenes and Related Organocatalysts

Editor(s): Tsutomu Ishikawa

Published Online: 3 FEB 2009

Print ISBN: 9780470518007

Online ISBN: 9780470740859

DOI: 10.1002/9780470740859

About this Book

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About The Product

Guanidines, amidines and phosphazenes have been attracting attention in organic synthesis due to their potential functionality resulting from their extremely strong basicity. They are also promising catalysts because of their potential for easy molecular modification, possible recyclability, and reduced or zero toxicity. Importantly, these molecules can be derived as natural products - valuable as scientists move towards "sustainable chemistry", where reagents and catalysts are derived from biomaterial sources.

Superbases for Organic Synthesis is an essential guide to these important molecules for preparative organic synthesis. Topics covered include the following aspects:

  • an introduction to organosuperbases
  • physicochemical properties of organic superbases
  • amidines and guanidines in organic synthesis
  • phosphazene: preparation, reaction and catalytic role
  • polymer-supported organosuperbases
  • application of organosuperbases to total synthesis
  • related organocatalysts: proton sponges and urea derivatives
  • amidines and guanidines in natural products and medicines

Superbases for Organic Synthesis is a comprehensive, authoritative and up-to-date guide to these important reagents for organic chemists, drug discovery researchers and those interested in the chemistry of natural products.

Table of contents

    1. You have free access to this content
    2. Chapter 3

      Amidines in Organic Synthesis (pages 49–91)

      Professor Tsutomu Ishikawa and Takuya Kumamoto

    3. Chapter 11

      Perspectives (pages 315–320)

      Professor Tsutomu Ishikawa and Davor Margetic

    4. You have free access to this content

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