The Pulmonary Endothelium: Function in health and disease

Copyright © 2009 John Wiley & Sons, Ltd

The Pulmonary Endothelium: Function in health and disease

Editor(s): Norbert F. Voelkel, Sharon Rounds

Published Online: 11 SEP 2009

Print ISBN: 9780470723616

Online ISBN: 9780470747490

DOI: 10.1002/9780470747490

About this Book

Product Information

About The Product

The Pulmonary Endothelium is a uniquely comprehensive compendium of our current knowledge of the pulmonary endothelium and is the first book dedicated specifically to the subject, offering insights into current and future approaches to management. The text provides the clinician with the most up-to-date information on one of the core physiological processes in airway disease and is an ideal point of reference for both postgraduates and professionals - specialist physicians in pulmonology and allergy and workers in biomedical and pharmaceutical research.

Table of contents

    1. You have free access to this content
      Front Matter (pages 1–19)

    1. You have free access to this content
      Colour Plates (pages c1–c16)

  3. Section I: Normal Pulmonary Endothelium. Structure, Function, Cell Biology

    1. Chapter 1

      Development of the Pulmonary Endothelium in Development of the Pulmonary Circulation: Vasculogenesis and Angiogenesis (pages 1–24)

      Margaret A. Schwarz and Ondine B. Cleaver

    2. Chapter 2

      Anatomy of the Pulmonary Endothelium (pages 25–32)

      Radu V. Stan

    3. Chapter 3

      Cadherins and Connexins in Pulmonary Endothelial Function (pages 33–50)

      Kaushik Parthasarathi and Sadiqa K. Quadri

    4. Chapter 4

      Pulmonary Endothelial Cell Interactions with the Extracellular Matrix (pages 51–72)

      Katie L. Grinnell and Elizabeth O. Harrington

    5. Chapter 5

      Pulmonary Endothelial Cell Calcium Signaling and Regulation of Lung Vascular Barrier Function (pages 73–88)

      Nebojsa Knezevic, Mohammad Tauseef and Dolly Mehta

    6. Chapter 6

      Pulmonary Endothelium and Nitric Oxide (pages 89–104)

      Yunchao Su and Edward R. Block

    7. Chapter 7

      Pulmonary Endothelial Cell Surface Metabolic Functions (pages 105–112)

      Usamah S. Kayyali and Barry L. Fanburg

    8. Chapter 8

      Cell Biology of Lung Endothelial Permeability (pages 113–127)

      Guochang Hu and Richard D. Minshall

    9. Chapter 9

      Lung Endothelial Phenotypes: Insights Derived from the Systematic Study of Calcium Channels (pages 129–142)

      Donna L. Cioffi, Songwei Wu and Troy Stevens

    10. Chapter 10

      Pulmonary Endothelial Interactions with Leukocytes and Platelets (pages 143–166)

      Rosana Souza Rodrigues and Guy A. Zimmerman

    11. Chapter 11

      Mesenchymal–Endothelial Interactions in the Control of Angiogenic, Inflammatory, and Fibrotic Responses in the Pulmonary Circulation (pages 167–183)

      Kurt R. Stenmark, Evgenia V. Gerasimovskaya, Neil Davie and Maria Frid

    12. Chapter 12

      Pulmonary Endothelium and Vasomotor Control (pages 185–202)

      Nikki L. Jernigan, Benjimen R. Walker and Thomas C. Resta

    13. Chapter 13

      Pulmonary Endothelial Progenitor Cells (pages 203–216)

      Bernard Thébaud and Mervin C. Yoder

    14. Chapter 14

      Bronchial Vasculature: The Other Pulmonary Circulation (pages 217–227)

      Elizabeth Wagner

    15. Chapter 15

      Mapping Protein Expression on Pulmonary Vascular Endothelium (pages 229–240)

      Kerri A. Massey and Jan E. Schnitzer

  4. Section II: Mechanisms and Consequences of Pulmonary Endothelial Cell Injury

    1. Chapter 16

      Pulmonary Endothelial Cell Death: Implications for Lung Disease Pathogenesis (pages 241–260)

      Qing Lu and Sharon Rounds

    2. Chapter 17

      Oxidant-Mediated Signaling and Injury in Pulmonary Endothelium (pages 261–285)

      Kenneth E. Chapman, Shampa Chatterjee and Aron B. Fisher

    3. Chapter 18

      Hypoxia and the Pulmonary Endothelium (pages 287–302)

      Matthew Jankowich, Gaurav Choudhary and Sharon Rounds

    4. Chapter 19

      Viral Infection and Pulmonary Endothelial Cells (pages 303–307)

      Norbert F. Voelkel

    5. Chapter 20

      Effects of Pressure and Flow on the Pulmonary Endothelium (pages 309–335)

      Wolfgang M. Kuebler

    6. Chapter 21

      Therapeutic Strategies to Limit Lung Endothelial Cell Permeability (pages 337–354)

      Rachel K. Wolfson, Gabriel Lang, Jeff Jacobson and Joe G. N. Garcia

    7. Chapter 22

      Targeted Delivery of Biotherapeutics to the Pulmonary Endothelium (pages 355–377)

      Vladimir R. Muzykantov

  5. Section III: Pulmonary Endothelium in Disease

    1. Chapter 23

      Endothelial Regulation of the Pulmonary Circulation in the Fetus and Newborn (pages 379–397)

      Yuansheng Gao and J. Usha Raj

    2. Chapter 24

      Genetic Insights into Endothelial Barrier Regulation in the Acutely Inflamed Lung (pages 399–415)

      Sumegha Mitra, Daniel Turner Lloveras, Shwu-Fan Ma and Joe G. N. Garcia

    3. Chapter 25

      Interactions of Pulmonary Endothelial Cells with Immune Cells and Platelets: Implications for Disease Pathogenesis (pages 417–436)

      Mark R. Nicolls, Rasa Tamosiuniene, Ashok N. Babu and Norbert F. Voelkel

    4. Chapter 26

      Role of the Endothelium in Emphysema: Emphysema – A Lung Microvascular Disease (pages 437–447)

      Norbert F. Voelkel and Ramesh Natarajan

    5. Chapter 27

      Pulmonary Endothelium and Pulmonary Hypertension (pages 449–460)

      Rubin M. Tuder and Serpil C. Erzurum

    6. Chapter 28

      Collagen Vascular Diseases and Pulmonary Endothelium (pages 461–469)

      Pradeep R. Raioc and Carlyne D. Cool

    7. Chapter 29

      Pulmonary Endothelium in Thromboembolism (pages 471–483)

      Irene M. Lang

    8. Chapter 30

      Pulmonary Endothelium and Malignancies (pages 485–490)

      Abu-Bakr Al-Mehdi

    1. You have free access to this content
      Epilogue (pages 491–493)

    1. You have free access to this content
      Index (pages 495–511)

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