Editor(s): Saura C. Sahu, Daniel A. Casciano

Published Online: 18 AUG 2009

Print ISBN: 9780470741375

Online ISBN: 9780470747803

DOI: 10.1002/9780470747803

About this Book

Nanomaterials - substances smaller than 100 nanometers in size - have been added in recent years to an increasing numbers of consumer products used in day-to-day life; in food packaging, medical devices, pharmaceuticals, cosmetics, odor-resistant textiles and household appliances. The extensive application of nanomaterials in a wide range of products for human use poses a potential for toxicity risk to human health and the environment. Such adverse effects of nanomaterials on human health have triggered the development of a new scientific discipline known as "nanotoxicity" - the study of the toxicity of nanomaterials.

Nanotoxicity: From in vivo and in vitro Models to Health Risks provides up-to-date state-of-the-art information presented by recognized experts in this emerging new field in toxicology. It discusses the safety evaluation of nanomaterials in foods, drugs, medical devices, cosmetics and other regulated products and its use in risk analysis for potential regulatory use. Topics covered include:

  • biomarkers for nanotoxicity assessment
  • nanotoxicity assessment by gene expression analysis
  • in vivo and in vitro models for nanotoxicity testing
  • mechanisms of nanotoxicity
  • pharmakokinetics of nanomaterials
  • nanotoxicity of foods including food processing, food packaging and food safety
  • nanotoxicity of drugs including drug development and drug delivery
  • nanotoxicity of cosmetics and consumer products
  • health and environmental impact of nanotoxicity
  • safety evaluation of nanomaterials
  • regulatory impact of nanomaterials

Nanotoxicity: From in vivo and in vitro Models to Health Risks is a valuable authoritative source of information for readers from a wide range of disciplines such as toxicology, pharmacology, drug toxicity and food and environmental sciences. The book will be useful to the research community in academia, industry, hospitals and government, as well as to government regulators and risk assessors of foods, drugs and environmental and agricultural products.

Table of contents

    1. You have free access to this content
    2. You have free access to this content
    3. Chapter 15

      In Vivo and In Vitro Models for Nanotoxicology Testing (pages 279–302)

      Rosalba Gornati, Elena Papis, Mario Di Gioacchino, Enrico Sabbioni, Isabella Dalle-Donne, Aldo Milzani and Giovanni Bernardini

    4. Chapter 17

      In Vitro and In Vivo Models for Nanotoxicity Testing (pages 335–348)

      Kyung O. Yu, Laura K. Braydich-Stolle, David M. Mattie, John J. Schlager and Saber M. Hussain

    5. Chapter 23

      Strategies for Risk Assessment of Nanomaterials (pages 499–518)

      Hae-Seong Yoon, Hyun-Kyung Kim, Dong Deuk Jang and Myung-Haing Cho

    6. Chapter 24

      Metal Nanoparticle Health Risk Assessment (pages 519–541)

      Mario Di Gioacchino, Nicola Verna, Rosalba Gornati, Enrico Sabbioni and Giovanni Bernardini

    7. You have free access to this content