Nanoplatform-Based Molecular Imaging

Copyright © 2011 John Wiley & Sons, Inc.

Nanoplatform-Based Molecular Imaging

Editor(s): Xiaoyuan Chen

Published Online: 25 MAY 2011 10:25AM EST

Print ISBN: 9780470521151

Online ISBN: 9780470767047

DOI: 10.1002/9780470767047

About this Book

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The cutting-edge guide on advancing the science of molecular imaging using nanoparticles

Nanoplathform-Based Molecular Imaging provides rationale for using nanoparticle-based probes for molecular imaging, then discusses general strategies for this underutilized, yet promising, technology. It addresses general strategies of particle synthesis and surface chemistry, applications in computed tomography optical imaging, magnetic resonance imaging, ultrasound, multimodality imaging, theranostics, and finally, the clinical perspectives of nanoimaging. This comprehensive volume summarizes the opinions of those in the forefront of research and describes the latest developments by emphasizing fundamentals and initiating hands-on application.

 

Table of contents

    1. You have free access to this content
      Frontmatter (pages i–xviii)

  2. Part I: Basics of Molecular Imaging and Nanobiotechnology

    1. Chapter 1

      Basic Principles of Molecular Imaging (pages 1–24)

      Sven H. Hausner

    2. Chapter 2

      Synthesis of Nanomaterials as a Platform for Molecular Imaging (pages 25–45)

      Jinhao Gao, Jin Xie, Bing Xu and Xiaoyuan Chen

    3. Chapter 3

      Nanoparticle Surface Modification and Bioconjugation (pages 47–73)

      Jin Xie, Jinhao Gao, Mark Michalski and Xiaoyuan Chen

    4. Chapter 4

      Biodistribution and Pharmacokinetics of Nanoprobes (pages 75–104)

      Nagesh Kolishetti, Frank Alexis, Eric M. Pridgen and Omid C. Farokhzad

  3. Part II: Nanoparticles for Single Modality Molecular Imaging

    1. Chapter 5

      Computed Tomography as a Tool for Anatomical and Molecular Imaging (pages 105–137)

      Pingyu Liu, Hu Zhou and Lei Xing

    2. Chapter 6

      Carbon Nanotube X-Ray for Dynamic Micro-CT Imaging of Small Animal Models (pages 139–158)

      Otto Zhou, Guohua Cao, Yueh Z. Lee and Jianping Lu

    3. Chapter 7

      Quantum Dots for In Vivo Molecular Imaging (pages 159–181)

      Yun Xing

    4. Chapter 8

      Biopolymer, Dendrimer, and Liposome Nanoplatforms for Optical Molecular Imaging (pages 183–196)

      David Pham, Ling Zhang, Bo Chen and Ella Fung Jones

    5. Chapter 9

      Nanoplatforms for Raman Molecular Imaging in Biological Systems (pages 197–216)

      Zhuang Liu

    6. Chapter 10

      Single-Walled Carbon Nanotube Near-Infrared Fluorescent Sensors for Biological Systems (pages 217–232)

      Jingqing Zhang and Michael S. Strano

    7. Chapter 11

      Microparticle- and Nanoparticle-Based Contrast-Enhanced Ultrasound Imaging (pages 233–262)

      Nirupama Deshpande and Jürgen K. Willmann

    8. Chapter 12

      Ultrasound-Based Molecular Imaging Using Nanoagents (pages 263–278)

      Srivalleesha Mallidi, Mohammad Mehrmohammadi, Kimberly Homan, Bo Wang, Min Qu, Timothy Larson, Konstantin Sokolov and Stanislav Emelianov

    9. Chapter 13

      MRI Contrast Agents Based on Inorganic Nanoparticles (pages 279–308)

      Hyon Bin Na and Taeghwan Hyeon

    10. Chapter 14

      Cellular Magnetic Labeling with Iron Oxide Nanoparticles (pages 309–331)

      Sébastien Boutry, Sophie Laurent, Luce Vander Elst and Robert N. Muller

    11. Chapter 15

      Nanoparticles Containing Rare Earth Ions: A Tunable Tool for MRI (pages 333–374)

      C. Rivière, S. Roux, R. Bazzi, J.-L. Bridot, C. Billotey, P. Perriat and O. Tillement

    12. Chapter 16

      Microfabricated Multispectral MRI Contrast Agents (pages 375–397)

      Gary Zabow and Alan Koretsky

    13. Chapter 17

      Radiolabeled Nanoplatforms: Imaging Hot Bullets Hitting their Target (pages 399–429)

      Raffaella Rossin

  4. Part III: Nanoparticle Platforms as Multimodality Imaging and Therapy Agents

    1. Chapter 18

      Lipoprotein-Based Nanoplatforms for Cancer Molecular Imaging (pages 431–462)

      Ian R. Corbin, Kenneth Ng and Gang Zheng

    2. Chapter 19

      Protein Cages as Multimode Imaging Agents (pages 463–480)

      Masaki Uchida, Lars Liepold, Mark Young and Trevor Douglas

    3. Chapter 20

      Biomedical Applications of Single-Walled Carbon Nanotubes (pages 481–528)

      Weibo Cai, Ting Gao and Hao Hong

    4. Chapter 21

      Multifunctional Nanoparticles for Multimodal Molecular Imaging (pages 529–540)

      Yanglong Hou and Rui Hao

    5. Chapter 22

      Multifunctional Nanoparticles for Cancer Theragnosis (pages 541–563)

      Seulki Lee, Ick Chan Kwon and Kwangmeyung Kim

    6. Chapter 23

      Nanoparticles for Combined Cancer Imaging and Therapy (pages 565–592)

      Vaishali Bagalkot, Mi Kyung YU and Sangyong Jon

    7. Chapter 24

      Multimodal Imaging and Therapy with Magnetofluorescent Nanoparticles (pages 593–613)

      Jason R. McCarthy and Ralph Weissleder

    8. Chapter 25

      Gold Nanocages: A Multifunctional Platform for Molecular Optical Imaging and Photothermal Treatment (pages 615–638)

      Leslie Au, Claire M. Cobley, Jingyi Chen and Younan Xia

    9. Chapter 26

      Theranostic Applications of Gold Nanoparticles in Cancer (pages 639–657)

      Parmeswaran Diagaradjane, Pranshu Mohindra and Sunil Krishnan

    10. Chapter 27

      Gold Nanorods as Theranostic Agents (pages 659–681)

      Alexander Wei, Qingshan Wei and Alexei P. Leonov

    11. Chapter 28

      Theranostic Applications of Gold Core–Shell Structured Nanoparticles (pages 683–708)

      Wei Lu, Marites P. Melancon and Chun Li

    12. Chapter 29

      Magnetic Nanoparticle Carrier for Targeted Drug Delivery: Perspective, Outlook, and Design (pages 709–724)

      R. D. K. Misra

    13. Chapter 30

      Perfluorocarbon Nanoparticles: A Multidimensional Platform for Targeted Image-Guided Drug Delivery (pages 725–753)

      Gregory M. Lanza, Shelton D. Caruthers, Anne H. Schmieder, Patrick M. Winter, Tillmann Cyrus and Samuel A. Wickline

    14. Chapter 31

      Radioimmunonanoparticles for Cancer Imaging and Therapy (pages 755–780)

      Arutselvan Natarajan

  5. Part IV: Translational Nanomedicine

    1. Chapter 32

      Current Status and Future Prospects for Nanoparticle-Based Technology in Human Medicine (pages 781–813)

      Nuria Sanvicens, Fátima Fernández, J.-Pablo Salvador and M.-Pilar Marco

    1. You have free access to this content
      Index (pages 815–823)

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