Organelle-Specific Pharmaceutical Nanotechnology

Copyright © 2010 John Wiley & Sons, Inc.

Organelle-Specific Pharmaceutical Nanotechnology

Editor(s): Volkmar Weissig, Gerard G. M. D'Souza

Published Online: 25 AUG 2010 11:17AM EST

Print ISBN: 9780470631652

Online ISBN: 9780470875780

DOI: 10.1002/9780470875780

About this Book

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About The Product

This book introduces and discusses the latest in biomedical research--Pharmaceutical Nanotechnology applied at the sub-cellular level.

Table of contents

    1. You have free access to this content
      Frontmatter (pages i–xiv)

    2. You have free access to this content
      Color Plates (pages c1–c32)

    3. Chapter 1

      An Introduction to Subcellular Nanomedicine: Current Trends and Future Developments (pages 1–13)

      Gerard G. M. D'Souza and Volkmar Weissig

    4. Chapter 2

      Delivery of Nanonsensors to Measure the Intracellular Environment (pages 15–33)

      Paul G. Coupland and Jonathan W. Aylott

    5. Chapter 3

      Cytoplasmic Diffusion of Dendrimers and Dendriplexes (pages 35–54)

      Alexander T. Florence and Pakatip Ruenraroengsak

    6. Chapter 4

      Endocytosis and Intracellular Trafficking of Quantum Dot–Ligand Bioconjugates (pages 55–72)

      Tore-Geir Iversen, Nadine Frerker and Kirsten Sandvig

    7. Chapter 5

      Synthesis of Metal Nanoparticle-Based Intracellular Biosensors and Therapeutic Agents (pages 73–91)

      Neil Bricklebank

    8. Chapter 6

      Subcellular Fate of Nanodelivery Systems (pages 93–121)

      Dusica Maysinger, Sebastien Boridy and Eliza Hutter

    9. Chapter 7

      Intracellular Fate of Plasmid DNA Polyplexes (pages 123–142)

      Kevin Maier and Ernst Wagner

    10. Chapter 8

      Intracellular Trafficking of Membrane Receptor-Mediated Uptake of Carbon Nanotubes (pages 143–159)

      Bin Kang and Yaodong Dai

    11. Chapter 9

      Real-Time Particle Tracking for Studying Intracellular Transport of Nanotherapeutics (pages 161–175)

      Clive Chen and Junghae Suh

    12. Chapter 10

      Tracking Intracellular Polymer Localization Via Fluorescence Microscopy (pages 177–192)

      Simon C. W. Richardson

    13. Chapter 11

      Can QSAR Models Describing Small-Molecule Xenobiotics Give Useful Tips for Predicting Uptake and Localization of Nanoparticles in Living Cells? And If Not, Why Not? (pages 193–206)

      Richard W. Horobin

    14. Chapter 12

      Self-Unpacking Gene Delivery Scaffolds (pages 207–230)

      Millicent O. Sullivan

    15. Chapter 13

      Cellular Trafficking of Dendrimers (pages 231–246)

      Yunus Emre Kurtoglu and Rangaramanujam M. Kannan

    16. Chapter 14

      Endolysosomolytically Active pH-Sensitive Polymeric Nanotechnology (pages 247–262)

      Han Chang Kang and You Han Bae

    17. Chapter 15

      Uptake and Intracellular Dynamics of Proteins Internalized by Cell-Penetrating Peptides (pages 263–288)

      Arwyn T. Jones

    18. Chapter 16

      Cargo Transport by Teams of Molecular Motors: Basic Mechanisms for Intracellular Drug Delivery (pages 289–309)

      Melanie J. I. Müller, Florian Berger, Stefan Klumpp and Reinhard Lipowsky

    19. Chapter 17

      The Potential of Photochemical Internalization (PCI) for the Cytosolic Delivery of Nanomedicines (pages 311–322)

      Kristian Berg, Anette Weyergang, Anders Høgset and Pål Kristian Selbo

    20. Chapter 18

      Peptide-Based Nanocarriers for Intracellular Delivery of Biologically Active Proteins (pages 323–336)

      Seong Loong Lo and Shu Wang

    21. Chapter 19

      Organelle-Specific Pharmaceutical Nanotechnology: Active Cellular Transport of Submicro- and Nanoscale Particles (pages 337–356)

      Galya Orr

    22. Chapter 20

      Subcellular Targeting of Virus-Envelope-Coated Nanoparticles (pages 357–383)

      Jia Wang, Mohammad F. Saeed, Andrey A. Kolokoltsov and Robert A. Davey

    23. Chapter 21

      Mitochondria-Targeted Pharmaceutical Nanocarriers (pages 385–401)

      Volkmar Weissig and Gerard G. M. D'Souza

    24. Chapter 22

      Cell-Penetrating Peptides for Cytosolic Delivery of Biomacromolecules (pages 403–432)

      Camilla Foged, Xiaona Jing and Hanne Moerck Nielsen

    25. Chapter 23

      Therapeutic Nano-Object Delivery to Subdomains of Cardiac Myocytes (pages 433–447)

      Valeriy Lukyanenko

    26. Chapter 24

      Design Parameters Modulating Intracellular Drug Delivery: Anchoring to Specific Cellular Epitopes, Carrier Geometry, and Use of Auxiliary Pharmacological Agents (pages 449–474)

      Silvia Muro and Vladimir R. Muzykantov

    27. Chapter 25

      Uptake Pathways Dependent Intracellular Trafficking of DNA Carrying Nanodelivery Systems (pages 475–506)

      Ikramy A. Khalil, Yuma Yamada, Hidetaka Akita and Hideyoshi Harashima

    28. Chapter 26

      Cellular Interactions of Plasmon-Resonant Gold Nanorods (pages 507–533)

      Qingshan Wei and Alexander Wei

    29. Chapter 27

      Quantum Dot Labeling for Assessment of Intracellular Trafficking of Therapeutically Active Molecules (pages 535–567)

      Diane J. Burgess and Mamta Kapoor

    30. You have free access to this content
      Index (pages 569–590)

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