ADMET for Medicinal Chemists: A Practical Guide
Copyright © 2011 John Wiley & Sons, Inc.
Editor(s): Katya Tsaioun, Steven A. Kates
Published Online: 29 NOV 2010 03:56PM EST
Print ISBN: 9780470484074
Online ISBN: 9780470915110
About this Book
This book guides medicinal chemists in how to implement early ADMET testing in their workflow in order to improve both the speed and efficiency of their efforts. Although many pharmaceutical companies have dedicated groups directly interfacing with drug discovery, the scientific principles and strategies are practiced in a variety of different ways. This book answers the need to regularize the drug discovery interface; it defines and reviews the field of ADME for medicinal chemists. In addition, the scientific principles and the tools utilized by ADME scientists in a discovery setting, as applied to medicinal chemistry and structure modification to improve drug-like properties of drug candidates, are examined.