ADMET for Medicinal Chemists: A Practical Guide

ADMET for Medicinal Chemists: A Practical Guide

Editor(s): Katya Tsaioun, Steven A. Kates

Published Online: 29 NOV 2010 03:56PM EST

Print ISBN: 9780470484074

Online ISBN: 9780470915110

DOI: 10.1002/9780470915110

About this Book

This book guides medicinal chemists in how to implement early ADMET testing in their workflow in order to improve both the speed and efficiency of their efforts. Although many pharmaceutical companies have dedicated groups directly interfacing with drug discovery, the scientific principles and strategies are practiced in a variety of different ways. This book answers the need to regularize the drug discovery interface; it defines and reviews the field of ADME for medicinal chemists. In addition, the scientific principles and the tools utilized by ADME scientists in a discovery setting, as applied to medicinal chemistry and structure modification to improve drug-like properties of drug candidates, are examined.

Table of contents

    1. You have free access to this content
    2. You have free access to this content
    3. Chapter 2

      In Silico ADME/Tox Predictions (pages 29–124)

      David Lagorce, Christelle Reynes, Anne-Claude Camproux, Maria A. Miteva, Olivier Sperandio and Bruno O. Villoutreix

    4. Chapter 4

      ADME (pages 145–200)

      Martin E. Dowty, Dean M. Messing, Yurong Lai and Leonid (Leo) Kirkovsky

    5. You have free access to this content

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