Advances in Enzymology and Related Areas of Molecular Biology

Copyright © 2011 John Wiley & Sons, Inc.

Advances in Enzymology and Related Areas of Molecular Biology

Editor(s): Eric J. Toone

Published Online: 23 FEB 2011 12:25PM EST

Print ISBN: 9780470638354

Online ISBN: 9780470920541

DOI: 10.1002/9780470920541

About this Book

This book covers important advances in enzymology, explaining the behavior of enzymes and how they can be utilized to develop novel drugs, synthesize known and novel compounds, and understand evolutionary processes.

Table of contents

    1. You have free access to this content
      Frontmatter (pages i–xiii)

    2. You have free access to this content
      Color Plates (pages c1–c8)

    3. Structure and Mechanism of RND-Type Multidrug Efflux Pumps (pages 1–60)

      Hiroshi Nikaido

    4. Efflux Pumps of Gram-Negative Bacteria: Genetic Responses to Stress and the Modulation of their Activity by pH, Inhibitors, and Phenothiazines (pages 61–108)

      Leonard Amaral, Seamus Fanning and Jean-Marie Pagès

    5. Efflux Pumps of the Resistance–Nodulation–Division Family: A Perspective of their Structure, Function, and Regulation in Gram-Negative Bacteria (pages 109–146)

      Mathew D. Routh, Yaramah Zalucki, Chih-Chia Su, Feng Long, Qijing Zhang, William M. Shafer and Edward W. Yu

    6. The MFS Efflux Proteins of Gram-Positive and Gram-Negative Bacteria (pages 147–166)

      Massoud Saidijam, Kim E. Bettaney, Dong Leng, Pikyee Ma, Zhiqiang Xu, Jeffrey N. Keen, Nicholas G. Rutherford, Alison Ward, Peter J. F. Henderson, Gerda Szakonyi, Qinghu Ren, Ian T. Paulsen, Ingerid Nes, Jasmin K. Kroeger and Anne-Brit Kolsto

    7. Efflux Pumps as an Important Mechanism for Quinolone Resistance (pages 167–235)

      Jordi Vila, Anna Fàbrega, Ignasi Roca, Alvaro Hernández and José Luis Martínez

    8. Xenobiotic Efflux in Bacteria and Fungi: A Genomics Update (pages 237–306)

      Ravi D. Barabote, Jose Thekkiniath, Richard E. Strauss, Govindsamy Vediyappan, Joe A. Fralick and Michael J. San Francisco

    9. A Survey of Oxidative Paracatalytic Reactions Catalyzed by Enzymes that Generate Carbanionic Intermediates: Implications for ROS Production, Cancer Etiology, and Neurodegenerative Diseases (pages 307–360)

      Victoria I. Bunik, John V. Schloss, John T. Pinto, Natalia Dudareva and Arthur J. L. Cooper

    10. You have free access to this content
      Author Index (pages 361–401)

    11. You have free access to this content
      Subject Index (pages 403–418)

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