RNA Interference: Application to Drug Discovery and Challenges to Pharmaceutical Development

RNA Interference: Application to Drug Discovery and Challenges to Pharmaceutical Development

Editor(s): Paul H. Johnson

Published Online: 30 NOV 2010 10:49AM EST

Print ISBN: 9780471771517

Online ISBN: 9780470923733

DOI: 10.1002/9780470923733

About this Book

RNA Interference: Application to Drug Discovery and Challenges to Pharmaceutical Development provides a general overview of this rapidly emerging field, with a strong emphasis on issues and aspects that are important to a drug development team. The first part covers more general background of RNA interference and its application in drug discovery. In the second part, the book addresses siRNA (small interfering RNA), a pharmaceutically potent form, and its use and delivery in therapeutics along with manufacturing and delivery aspects.

Table of contents

    1. You have free access to this content
    1. You have free access to this content
  1. Part I: Biology of RNA Interference

  2. Part II: Development of SiRNA for Therapeutic Applications

    1. Chapter 5

      Discovery of New SiRNA Delivery Agents (pages 123–173)

      Paul H. Johnson, Diane Frank, Kunyuan Cui, Roger Adami, Harry Wang, Michael Houston and Steven C. Quay

    1. You have free access to this content

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