Clinical Pancreatology: For Practising Gastroenterologists and Surgeons

Copyright © 2005 by Blackwell Publishing Ltd

Clinical Pancreatology: For Practising Gastroenterologists and Surgeons

Editor(s): J. Enrique Domínguez-Muñoz, Peter Malfertheiner

Published Online: 25 OCT 2007

Print ISBN: 9781405122764

Online ISBN: 9780470987506

DOI: 10.1002/9780470987506

About this Book

Product Information

About The Product

Most patients suffering from pancreatic diseases are managed by general internists, gastroenterologists and/or surgeons in non-specialized centers. Basic and clinical research in pancreatology is continuously leading to changes in the management of pancreatic diseases, but these advances are applied to the clinical practice almost exclusively in specialized centers by specialized groups.

The books and journals currently available are directed at pancreatologists and the information does not reach most general clinicians and surgeons who treat patients suffering from pancreatic diseases. The aim of this book is to provide practising gastroenterologists and surgeons with clear information regarding the diagnosis and treatment of pancreatic diseases.

Table of contents

    1. You have free access to this content
      Frontmatter (pages i–xix)

  2. Part I: Acute Pancreatitis

    1. Chapter 1

      Acute Pancreatitis: Definition and Classification for Clinical Practice (pages 1–9)

      Edward L. Bradley

    2. Chapter 2

      Pathogenesis: How Does Acute Pancreatitis Develop? (pages 10–26)

      Michael L. Steer and George Perides

    3. Chapter 3

      Pathophysiology of Acute Pancreatitis: Which Events are Clinically Relevant? (pages 27–33)

      Miguel Pérez-Mateo and Juan Martínez

    4. Chapter 4

      How Should Acute Pancreatitis Be Diagnosed in Clinical Practice? (pages 34–39)

      Richard S. Kwon and Peter A. Banks

    5. Chapter 5

      Guidelines for the Detection of the Etiologic Factor of Acute Pancreatitis (pages 40–46)

      J. Enrique Domínguez-Muñoz

    6. Chapter 6

      Early Prognostic Evaluation of Acute Pancreatitis: Why and How Should Severity Be Predicted? (pages 47–55)

      J. Enrique Domínguez-Muñoz

    7. Chapter 7

      Role of Imaging Methods in Acute Pancreatitis: Diagnosis, Staging, and Detection of Complications (pages 56–80)

      Emil J. Balthazar and Glenn Krinsky

    8. Chapter 8

      Basis of Therapy in Acute Pancreatitis (pages 81–86)

      Clement W. Imrie

    9. Chapter 9

      Guidelines for the Treatment of Pain in Acute Pancreatitis (pages 87–94)

      Juan Martínez and Miguel Pérez-Mateo

    10. Chapter 10

      Nutrition in the Acute Phase of Pancreatitis: Why, When, How, and How Long? (pages 95–101)

      Konstantina Paraskeva, Costas Avgerinos and Christos Dervenis

    11. Chapter 11

      Antibiotic Prophylaxis for Acute Pancreatitis in Clinical Practice: Rationale, Indications, and Protocols for Clinical Practice (pages 102–105)

      Giovanni Butturini, Roberto Salvia, Nora Sartori and Claudio Bassi

    12. Chapter 12

      Modulation of the Inflammatory Response in Acute Pancreatitis: What Can Be Expected? (pages 106–112)

      Colin J. McKay

    13. Chapter 13

      Early Endoscopic Sphincterotomy in Acute Pancreatitis: Is it Indicated, Advisable, Not Indicated, or Contraindicated? A Proposal for Clinical Practice (pages 113–124)

      Jennifer Barro, Roy M. Soetikno and David L. Carr-Locke

    14. Chapter 14

      Indications for Surgery in Acute Pancreatitis (pages 125–132)

      Oscar Joe Hines and Howard A. Reber

    15. Chapter 15

      Surgical Approaches to Acute Necrotizing Pancreatitis (pages 133–140)

      Laureano Fernández-Cruz and Hans G. Beger

    16. Chapter 16

      Management of Acute Pancreatic Pseudocyst: When to Observe, When and How to Drain (pages 141–148)

      René Laugier

    17. Chapter 17

      Therapeutic Approach to Pancreatic Abscess (pages 149–155)

      Luis Sabater-Ortí, Julio Calvete-Chornet and Salvador Lledó-Matoses

    18. Chapter 18

      Is There a Place for Laparoscopic Surgery in the Management of Acute Pancreatitis? (pages 156–165)

      Gregorio Castellanos, Antonio Piñero and Pascual Parrilla

    19. Chapter 19

      What Should Be Done to Prevent Relapses of Acute Pancreatitis? (pages 166–175)

      Karlheinz Kiehne and Ulrich R. Fölsch

    20. Chapter 20

      Treatment of Acute Pancreatitis in Clinical Practice: A Global View (pages 176–179)

      J. Enrique Domínguez-Muñoz

  3. Part II: Chronic Pancreatitis and Cystic Fibrosis

    1. Chapter 21

      Chronic Pancreatitis: Definition and Classification for Clinical Practice (pages 180–186)

      Peter Layer and Ulrike Melle

    2. Chapter 22

      Epidemiology of Chronic Pancreatitis: An Infrequent Disease or an Infrequently Diagnosed Disease? (pages 187–191)

      Salvador Navarro and Antonio Soriano

    3. Chapter 23

      Etiopathogenesis of Chronic Pancreatitis: A Genetic Disease with Some Precipitating Factors? (pages 192–200)

      Georgios I. Papachristou and David C. Whitcomb

    4. Chapter 24

      Pathophysiology of Chronic Pancreatitis (pages 201–213)

      Frank Ulrich Weiss and Markus M. Lerch

    5. Chapter 25

      What is Clinically Relevant About the Genetics of Cystic Fibrosis? (pages 214–219)

      Harry Cuppens

    6. Chapter 26

      How Does Alcohol Damage the Pancreas? (pages 220–228)

      Tomas Hucl, Alexander Schneider and Manfred V. Singer

    7. Chapter 27

      Why is Chronic Pancreatitis So Difficult to Detect? Key Clinical Aspects for an Early Diagnosis (pages 229–235)

      Paul G. Lankisch and Bernhard Lembcke

    8. Chapter 28

      Role of Imaging Methods in Diagnosing, Staging, and Detecting Complications of Chronic Pancreatitis in Clinical Practice: Should MRCP and MRI Replace ERCP and CT? (pages 236–245)

      Carmen Villalba-Martín and J. Enrique Domínguez-Muñoz

    9. Chapter 29

      The Place of Endoscopic Ultrasound in the Diagnosis of Chronic Pancreatitis (pages 246–252)

      Stefan Kahl and Peter Malfertheiner

    10. Chapter 30

      Should Histology and/or Cytology be the Gold Standard for the Diagnosis of Chronic Pancreatitis in Clinical Practice? (pages 253–258)

      Dale E. Bockman

    11. Chapter 31

      Pancreatic Function Tests for Diagnosis and Staging of Chronic Pancreatitis, Cystic Fibrosis, and Exocrine Pancreatic Insufficiency of Other Etiologies: Which Tests are Necessary and How Should They be Performed in Clinical Routine? (pages 259–266)

      J. Enrique Domínguez-Muñoz

    12. Chapter 32

      Follow-Up of Patients with Chronic Pancreatitis: What to Do and Which Complications Can Be Expected (pages 267–272)

      Lucio Gullo and Raffaele Pezzilli

    13. Chapter 33

      Conservative Treatment of Pain in Chronic Pancreatitis: Guidelines for Clinical Routine (pages 273–279)

      Pierluigi Di Sebastiano, Markus A. Weigand, Jörg Köninger, Fabio F. di Mola, Helmut Friess and Markus W. Büchler

    14. Chapter 34

      Endoscopic Treatment of Pain in Chronic Pancreatitis: Really Useful or Only Feasible? (pages 280–287)

      Guido Costamagna and Andrea Tringali

    15. Chapter 35

      Management of Maldigestion in Chronic Pancreatitis: A Practical Protocol (pages 288–293)

      J. Enrique Domínguez-Muñoz

    16. Chapter 36

      Management of Maldigestion in Cystic Fibrosis: Tricks for an Adequate Outcome (pages 294–298)

      Luisa Guarner

    17. Chapter 37

      Management of Exocrine Pancreatic Insufficiency Associated With Other Clinical Conditions: Gastrointestinal Surgery, Diabetes Mellitus, AIDS (pages 299–305)

      Julio Iglesias-García

    18. Chapter 38

      Indications and Timing of Surgery in Chronic Pancreatitis (pages 306–314)

      Werner Hartwig, Jens Werner, Markus W. Büchler and Waldemar Uhl

    19. Chapter 39

      Surgical Approaches to Chronic Pancreatitis: Technical Implications and Outcome (pages 315–322)

      Hans G. Beger, Bernd Mühling, Naoki Hiki, Zhengfei Zhou, Zhanbing Liu and Bertram Poch

    20. Chapter 40

      Management of Chronic Pancreatic Pseudocyst: When to Observe, When and How to Drain (pages 323–330)

      William R. Brugge

  4. Part III: Pancreatic Cancer

    1. Chapter 41

      What is the Epidemiologic Impact of Pancreatic Cancer? (pages 331–350)

      Joachim Mössner

    2. Chapter 42

      Molecular Basis of Pancreatic Carcinogenesis: Which Concepts May Be Clinically Relevant? (pages 351–358)

      Martin Wirtz, Joanne Nyarangi, Jörg Köninger and Helmut Friess

    3. Chapter 43

      Genetic Basis of Pancreatic Carcinogenesis: Which Concepts May Be Clinically Relevant? (pages 359–365)

      Felix Lluis

    4. Chapter 44

      Clinical Assessment of Pancreatic Cancer: Is there a Chance for Early Diagnosis? (pages 366–376)

      Parviz M. Pour

    5. Chapter 45

      What Can Be Expected from Tumor Markers in Pancreatic Cancer? (pages 377–382)

      Thomas Seufferlein and Guido Adler

    6. Chapter 46

      Stage Classification of Pancreatic Cancer (pages 383–387)

      Antonio Farré

    7. Chapter 47

      Imaging Diagnosis and Staging of Pancreatic Cancer: Which Methods are Essential? (pages 388–401)

      Marchelle J. Bean, Karen M. Horton and Elliot K. Fishman

    8. Chapter 48

      The Role of Endoscopic Ultrasound in the Diagnosis and Assessment of the Resectability of Pancreatic Cancer (pages 402–413)

      Marc Giovannini

    9. Chapter 49

      Pancreatic Cancer: Do We Need a Tissue Diagnosis in Order to Proceed with Resection? (pages 414–418)

      Matthew M. Hutter and Andrew L. Warshaw

    10. Chapter 50

      Staging Laparoscopy and Peritoneal Cytology in Pancreatic Cancer (pages 419–424)

      Ramon E. Jimenez and Carlos Fernández-del Castillo

    11. Chapter 51

      Management of Pain in Pancreatic Cancer: An Algorithm for Clinical Routine (pages 425–434)

      Åke Andrén-Sandberg

    12. Chapter 52

      What is the Optimal Surgical Treatment for Resectable Pancreatic Cancer? (pages 435–443)

      Beat M. Künzli, Helmut Friess and Markus W. Büchler

    13. Chapter 53

      Adjuvant and Neoadjuvant Treatment of Resectable Pancreatic Cancer: What is Worth Attempting? (pages 444–454)

      Michael G.T. Raraty, Paula Ghaneh and John P. Neoptolemos

    14. Chapter 54

      The Role of Endoscopy in the Management of Unresectable Pancreatic Cancer (pages 455–464)

      Richard A. Kozarek

    15. Chapter 55

      Palliative Chemotherapy And/Or Radiotherapy for Pancreatic Cancer: What Can Be Expected? (pages 465–471)

      Matthias Löhr and Frederik Wen

    16. Chapter 56

      Novel Treatments and Gene Therapy in Pancreatic Cancer (pages 472–478)

      Matthias Löhr and Nicholas R. Lemoine

  5. Part IV: Cystic Tumors of the Pancreas

    1. Chapter 57

      Spectrum and Classification of Cystic Tumors of the Pancreas (pages 479–487)

      Markus Kosmahl and GüNter Klöppel

    2. Chapter 58

      Diagnosis and Differential Diagnosis of Pancreatic Cystic Tumors (pages 488–496)

      Roberto Salvia, Isabella Frigerio, Claudio Bassi, Massimo Falconi and Paolo Pederzoli

    3. Chapter 59

      The Role of Endoscopic Ultrasonography in the Diagnosis and Management of Cystic Tumors of the Pancreas (pages 497–503)

      Enrique Vazquez-Sequeiros and Julio Iglesias-García

    4. Chapter 60

      Therapeutic Approach to Cystic Tumors (pages 504–512)

      Laureano Fernández-Cruz, Isidro Martínez, Rosa Gelabert, Gleydson Cesar-Borges, Emiliano Astudillo and Salvador Navarro

    1. You have free access to this content
      Index (pages 513–535)

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