The Vulnerable Atherosclerotic Plaque: Strategies for Diagnosis and Management

Copyright © 2007 by Blackwell Publishing

The Vulnerable Atherosclerotic Plaque: Strategies for Diagnosis and Management

Editor(s): Renu Virmani, Jagat Narula, Martin B. Leon, James T. Willerson

Published Online: 4 OCT 2007

Print ISBN: 9781405158596

Online ISBN: 9780470987575

DOI: 10.1002/9780470987575

About this Book

Product Information

About The Product

Finally, a convenient, one-volume summary of current knowledge on an area of increasing importance! The Vulnerable Atherosclerotic Plaque presents contributions from the best investigators in the field, skillfully edited for easy reading and lavishly illustrated with high-quality, full-color images.

After a considered and concise introduction, the book concentrates on:


  • Pathology of vulnerable plaque
  • Triggers for plaque rupture
  • Imaging of unstable plaque
  • Management of vulnerable plaques

Careful editing allows the authors to avoid repetition and provide comprehensive coverage of pathology, detection, and management. This thorough and authoritative reference will change the way interventionists look at the disease.

Table of contents

    1. You have free access to this content
      Frontmatter (pages i–ix)

  2. Part 1: Introduction

    1. Chapter 1

      History of Atherosclerosis and Vulnerable Plaque Research (pages 1–17)

      Mohammad Madjid, Ibrahim Aboshady, Samuel Ward Casscells, Renu Virmani and James T Willerson

  3. Part 2: Pathology

    1. Chapter 2

      The Pathology of Vulnerable Plaque (pages 19–36)

      Renu Virmani, Allen P Burke, James T Willerson, Andrew Farb, Jagat Narula and Frank D Kolodgie

    2. Chapter 3

      Plaque Rupture (pages 37–59)

      Renu Virmani, Allen P Burke, Andrew Farb, Herman K Gold, Aloke V Finn and Frank D Kolodgie

    3. Chapter 4

      Plaque Erosion (pages 60–76)

      Frank D Kolodgie, Allen P Burke, Andrew Farb, David R Fowler, Robert Kutys, Thomas N Wight and Renu Virmani

    4. Chapter 5

      Pathogenesis and Significance of Calcification in Coronary Atherosclerosis (pages 77–94)

      Allen P Burke, Frank D Kolodgie, Andrew Farb and Renu Virmani

    5. Chapter 6

      Adventitial and Periadventitial Fat Inflammation and Plaque Vulnerability (pages 95–104)

      Silvio Litovsky, Deborah Vela, Mohammad Madjid, Samuel Ward Casscells and James T Willerson

    6. Chapter 7

      Murine Models of Advanced Atherosclerosis (pages 105–127)

      Michael E Rosenfeld and Stephen M Schwartz

  4. Part 3: Triggers for plaque rupture

    1. Chapter 8

      Physical and Mechanical Stress (pages 129–139)

      Luis E Rohde and Richard T Lee

    2. Chapter 9

      Inflammation and Matrix Metalloproteinases (pages 140–161)

      Zorina S Galis and Susan M Lessner

    3. Chapter 10

      Apoptosis in Atherosclerosis (pages 162–183)

      Mark M Kockx, Wim Martinet and Michiel Knaapen

  5. Part 4: Diagnosis

    1. Chapter 11

      Emerging Biomarkers of Instability (pages 185–210)

      Sotirios Tsimikas

    2. Chapter 12

      Ultrasonic Detection of Coronary Disease (pages 211–221)

      Mani A Vannan, Chowdhury Ahsan, Johan Verjans, Artiom Petrov and Jagat Narula

    3. Chapter 13

      Intravascular Ultrasound for Plaque Characterization (pages 222–229)

      D Geoffrey Vince and Anuja Nair

    4. Chapter 14

      Magnetic Resonance Imaging and Intravascular Magnetic Resonance Imaging (pages 230–246)

      Hee Kwon Song, Ronald L Wolf, Jacob Schneiderman and Robert L Wilensky

    5. Chapter 15

      Radionuclide Imaging (pages 247–256)

      Johan Verjans and Jagat Narula

    6. Chapter 16

      Near-Infrared Spectroscopy (pages 257–262)

      Pedro R Moreno, Barbara Marshik and James E Muller

    7. Chapter 17

      Intravascular Thermography (pages 263–272)

      Mohammad Madjid, Morteza Naghavi, Silvio Litovsky, Samuel Ward Casscells and James T Willerson

    8. Chapter 18

      Optical Coherence Tomography (pages 273–288)

      Paul Magnin and Evelyn Regar

    9. Chapter 19

      Intravascular Palpography (pages 289–296)

      Johannes A Schaar, Chris L de Korte, Frits Mastik, Pime de Feyter, Cornelis J Slager, Anton FW van der Steen and Patrick W Serruys

    10. Chapter 20

      Coronary Computed Tomography for the Detection of Atherosclerotic Plaque Burden (pages 297–302)

      Allen J Taylor and Irwin M Feuerstein

  6. Part 5: Management

    1. Chapter 21

      New Developments in Treatment of Vulnerable Plaques (pages 303–320)

      Mohammad Madjid, Silvio Litovsky, James T Willerson and Samuel Ward Casscells

    2. Chapter 22

      Photodynamic Therapy (pages 321–330)

      Ron Waksman and Pauline E McEwan

    3. Chapter 23

      Thermal Stabilization of Vulnerable Plaques (pages 331–342)

      Samuel Ward Casscells, Birendra N Lal, Mohammad Madjid, Tarun Tewatia, Ibrahim Aboshady, Yong-Jian Geng and James T Willerson

    4. Chapter 24

      An Interventionalist's Perspective (pages 343–349)

      Aloke V Finn, Ronald Waksman and Herman Gold

    5. Chapter 25

      Genetic Modulation of Vulnerable Plaques (pages 350–367)

      Chunming Dong and Pascal J Goldschmidt-Clermont

    1. You have free access to this content
      Index (pages 369–375)

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