Cortical Development: Genes and Genetic Abnormalities: Novartis Foundation Symposium 288

Cortical Development: Genes and Genetic Abnormalities: Novartis Foundation Symposium 288

Editor(s): Gregory Bock, Jamie Goode

Published Online: 1 FEB 2008

Print ISBN: 9780470060926

Online ISBN: 9780470994030

DOI: 10.1002/9780470994030

Series Editor(s): Novartis Foundation

About this Book

To understand the brain and its devastating diseases, we need to reveal the mechanisms that produce it and the ways in which it can constantly change throughout a lifetime.  This book features a timely and insightful discussion between developmental neurobiologists and clinicians who deal with disorders of the nervous system.

Chapters in this book deal specifically with cell fate determination, cell migration and disorders of cell migration; current concepts and new ideas about cortical arealisation, and disorders which can arise from incorrect arealisation; genes implicated in the development of cortical connectivity and related pathologies such as schizophrenia and synaesthesia; and susceptibility genes for cognitive disorders such as schizophrenia, autism, dyslexia, and attention deficit disorder.

Table of contents

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    2. Regulation of Laminar and Area Patterning of Mammalian Neocortex and Behavioural Implications (pages 141–164)

      Dennis D. M. O'Leary, Shen-Ju Chou, Tadashi Hamasaki, Setsuko Sahara, Akihide Takeuchi, Sandrine Thuret and Axel Leingärtner

    3. Molecular Mechanisms of Thalamocortical Axon Targeting (pages 199–211)

      Nobuhiko Yamamoto, Takuro Maruyama, Naofumi Uesaka, Yasufumi Hayano, Makoto Takemoto and Akito Yamada

    4. Genes Involved in the Formation of the Earliest Cortical Circuits (pages 212–229)

      Zoltán Molnár, Anna Hoerder-Suabedissen, Wei Zhi Wang, Jamin DeProto, Kay Davies, Sheena Lee, Erin C. Jacobs, Anthony T. Campagnoni, Ole Paulsen, Maria Carmen Piñon and Amanda F. P. Cheung

    5. Emx and Nfi Genes Regulate Cortical Development and Axon Guidance in the Telencephalon (pages 230–245)

      Michael Piper, Amber-Lee S. Dawson, Charlotta Lindwall, Guy Barry, Céline Plachez and Linda J. Richards

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