Zebrafish: Methods for Assessing Drug Safety and Toxicity

Zebrafish: Methods for Assessing Drug Safety and Toxicity

Editor(s): Patricia McGrath

Published Online: 14 DEC 2011 11:49AM EST

Print ISBN: 9780470425138

Online ISBN: 9781118102138

DOI: 10.1002/9781118102138

About this Book

Zebrafish: Methods for Assessing Drug Safety and Toxicity offers a practical guide for using zebrafish as a tool for toxicology studies. 

Consolidating key protocols and approaches to help researchers navigate the important and evolving field of zebrafish models for toxicity screening, this new title describes the methods for using the zebrafish as a model organism to assess compound-induced toxicity on all major organs.  Individual chapters that concentrate on assays for each organ system are included and various analytical tools including microscopy, microplate readers, high content imaging systems, ECG, blood pressure monitors, high speed video and motion detectors are described.

Table of contents

    1. You have free access to this content
    2. You have free access to this content
    3. Chapter 2

      Developmental Toxicity Assessment in Zebrafish (pages 15–25)

      Maryann Haldi, Maegan Harden, Louis D'Amico, Anthony DeLise and Wen Lin Seng

    4. Chapter 13

      Zebrafish: A Predictive Model for Assessing Seizure Liability (pages 165–175)

      Demian Park, Joshua Meidenbauer, Breanne Sparta, Wen Lin Seng and Patricia McGrath

    5. Chapter 19

      Cytoprotective Activities of Water-Soluble Fullerenes in Zebrafish Models (pages 257–281)

      Florian Beuerle, Patrick Witte, Uwe Hartnagel, Russell Lebovitz, Chuenlei Parng and Andreas Hirsch

    6. Chapter 20

      Fishing to Design Inherently Safer Nanoparticles (pages 283–293)

      Lisa Truong, Michael T. Simonich, Katerine S. Saili and Robert L. Tanguay

    7. You have free access to this content

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