Advances in Enzymology: And Related Areas of Molecular Biology

Advances in Enzymology: And Related Areas of Molecular Biology

Editor(s): Eric J. Toone

Published Online: 13 OCT 2011 07:41AM EST

Print ISBN: 9781118014288

Online ISBN: 9781118105771

DOI: 10.1002/9781118105771

About this Book

This book covers important advances in enzymology, explaining the behavior of enzymes and how they can be utilized to develop novel drugs, synthesize known and novel compounds, and understand evolutionary processes. Advances in Enzymology focuses on enzymes, the primary catalysts of life processes. The explanation of the behavior of enzymes can be found via studies of their chemical mechanisms and can be utilized to develop novel drugs, synthesize known and novel compounds, and understand evolutionary processes. The transglutaminases, first described in 1957, are a large, widely-distributed family of enzymes canonically responsible for the amidation/transamidation of protein side chains. The extraordinary diversity of names associated with various enzymatic activities now recognized and aggregated as transglutaminase bears witness to the remarkable diversity of biological roles associated with the activity, including myriad human diseases.

Table of contents

    1. You have free access to this content
    2. You have free access to this content
    3. Transglutaminase 2 at the Crossroads between Cell Death and Survival (pages 197–246)

      Mauro Piacentini, Manuela D'Eletto, Laura Falasca, Maria Grazia Farrace and Carlo Rodolfo

    4. Irreversible Inhibitors of Tissue Transglutaminase (pages 415–447)

      Jeffrey W. Keillor, Nicolas Chabot, Isabelle Roy, Amina Mulani, Olivier Leogane and Christophe Pardin

    5. You have free access to this content

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