Radiochemical Syntheses: Radiopharmaceuticals for Positron Emission Tomography, Volume 1

Radiochemical Syntheses: Radiopharmaceuticals for Positron Emission Tomography, Volume 1

Editor(s): Peter J. H. Scott, Brian G. Hockley

Published Online: 4 JAN 2012 09:49AM EST

Print ISBN: 9780470588956

Online ISBN: 9781118140345

DOI: 10.1002/9781118140345

About this Book

The ultimate reference guide to the synthesis of radiopharmaceuticals

The Radiochemical Syntheses series provides scientists and professionals with a comprehensive reference to proven synthetic methods for radiochemical reactions, along with step-by-step guidance on how to replicate these syntheses in the laboratory.

Volume 1 in the series focuses on the synthesis and purification of radiopharmaceuticals in clinical use today. It brings together in one complete, self-contained volume a collection of monographs containing a wealth of practical information from across the literature, demonstrating in meticulous detail how to prepare radiopharmaceuticals for positron emission tomography (PET) imaging, especially in tumor studies, cardiology, and neuroscience.

Readers have key experimental details culled from the literature at their fingertips, greatly simplifying the process of qualifying a site for the clinical production of new radiopharmaceuticals.

Table of contents

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  1. Part I: Fluorine-18 Labeled Radiopharmaceuticals

    1. Chapter 3

      Radiosynthesis of 3′-Deoxy-3′-[18F]Fluorothymidine ([18F]FLT) (pages 21–30)

      Hartmuth C. Kolb, Henry C. Padgett, Steve Zigler, Jim Patanella, Fanrong Mu, Umesh B. Gangadharmath, Vani P. Mocharla, Peter J. H. Scott and Joseph C. Walsh

    2. Chapter 5

      Synthesis of [18F]Fluoromisonidazole (1-(2-Hydroxy-3-[18F]Fluoropropyl)-2-Nitroimidazole, [18F]FMISO) (pages 41–49)

      Patrick J. Riss, Valentina Ferrari, Robert Bielik, Roberto Canales-Candela, Rob Smith and Franklin I. Aigbirhio

    3. Chapter 6

      Synthesis of [18F]FPPRGD2 (pages 51–60)

      Shuanglong Liu, Frederick T. Chin, Zhen Cheng and Xiaoyuan Chen

    4. Chapter 11

      Synthesis of [18F]-Fallypride (pages 95–102)

      Laurent Brichard, Valentina Ferrari, Rob Smith and Franklin I. Aigbirhio

    5. Chapter 13

      Synthesis of [18F]Flumazenil ([18F]FZ) (pages 111–123)

      Ralf Schirrmacher, Alexey Kostikov, Gassan Massaweh, Miriam Kovacevic, Carmen Wängler and Alexander Thiel

  2. Part II: Carbon-11 Labeled Radiopharmaceuticals

    1. Chapter 19

      Synthesis of [11C]-meta-Hydroxyephedrine ([11C]MHED) (pages 191–198)

      Filippo Lodi, Assunta Carpinelli, Claudio Malizia and Stefano Boschi

    2. Chapter 22

      Synthesis of [11C]Flumazenil([11C]FMZ) (pages 221–231)

      Roberto Canales-Candela, Patrick J. Riss and Franklin I. Aigbirhio

    3. Chapter 26

      Synthesis of [carbonyl-11C]Way-100635 (pages 265–273)

      Jan D. Andersson, Sangram Nag, Raisa N. Krasikova, Victor W. Pike and Christer Halldin

  3. Part III: Other Radiopharmaceuticals

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    1. You have free access to this content

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