The AH Receptor in Biology and Toxicology

The AH Receptor in Biology and Toxicology

Editor(s): Raimo Pohjanvirta

Published Online: 10 NOV 2011 09:54AM EST

Print ISBN: 9780470601822

Online ISBN: 9781118140574

DOI: 10.1002/9781118140574

About this Book

This book provides a thorough and up-to-date overview of the aryl hydrocarbon receptor (AHR) and its unique dual role in toxicology and biology. The coverage includes epigenetic mechanisms, gene expression, reproductive and developmental toxicity, signal transduction, and transgenic animal models. Featuring an internationally recognized team of authors at the forefront of AHR research, this resource provides a comprehensive reference for readers interested in understanding the full spectrum of AHR, from basic concepts, toxicology analysis, and models to polymorphism and related diseases.

Table of contents

    1. You have free access to this content
    1. You have free access to this content
  1. Part I: Historical Background

  2. Part II: AHR as a Ligand-Activated Transcription Factor

    1. Chapter 4

      AHR Ligands: Promiscuity in Binding and Diversity in Response (pages 63–79)

      Danica DeGroot, Guochun He, Domenico Fraccalvieri, Laura Bonati, Allesandro Pandini and Michael S. Denison

  3. Part III: AHR as a Mediator of Xenobiotic Toxicities: Dioxins as a Key Example

    1. Chapter 12

      Role of the AHR and its Structure in TCDD Toxicity (pages 179–196)

      Raimo Pohjanvirta, Merja Korkalainen, Ivy D. Moffat, Paul C. Boutros and Allan B. Okey

  4. Part IV: AHR as a Physiological Regulator

    1. Chapter 33

      The AHR Regulates Cell Adhesion and Migration by Interacting with Oncogene and Growth Factor-Dependent Signaling (pages 485–497)

      Angel Carlos Roman, Jose M. Carvajal-Gonzalez, Sonia Mulero-Navarro, Aurea Gomez-Duran, Eva M. Rico-Leo, Jaime M. Merino and Pedro M. Fernandez-Salguero

    1. You have free access to this content