Analysis of Aggregates and Particles in Protein Pharmaceuticals

Analysis of Aggregates and Particles in Protein Pharmaceuticals

Editor(s): Hanns-Christian Mahler, Wim Jiskoot

Published Online: 13 JAN 2012 09:53AM EST

Print ISBN: 9780470497180

Online ISBN: 9781118150573

DOI: 10.1002/9781118150573

About this Book

This book describes how to address the analysis of aggregates and particles in protein pharmaceuticals, provides a comprehensive overview of current methods and integrated approaches used to quantify and characterize aggregates and particles, and discusses regulatory requirements. Analytical methods covered in the book include separation, light scattering, microscopy, and spectroscopy.

Table of contents

    1. You have free access to this content
    1. You have free access to this content
  1. Section I: Methods Used for Detecting, Quantifying, and Sizing of Protein Aggregates and Particles

    1. Chapter 7

      Characterization of Aggregates and Particles Using Emerging Techniques (pages 133–167)

      Hui Zhao, Manuel Diez, Atanas Koulov, Mariola Bozova, Markus Bluemel and Kurt Forrer

  2. Section II: Methods Used to Characterize Protein Aggregates and Particles

  3. Section III: Integrated Approaches to Protein Aggregation and Particles

    1. Chapter 14

      Protein Purification and its Relation to Protein Aggregation and Particles (pages 335–367)

      Roberto Falkenstein, Stefan Hepbildikler, Wolfgang Kuhne, Thorsten Lemm, Hans Rogl, Eva Rosenberg, Gerhard Winter, Frank Zettl and Ralf Zippelius

    1. You have free access to this content

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