Antibody-Mediated Drug Delivery Systems: Concepts, Technology, and Applications

Copyright © 2012 John Wiley & Sons, Inc.

Antibody-Mediated Drug Delivery Systems: Concepts, Technology, and Applications

Editor(s): Yashwant Pathak, Simon Benita

Published Online: 23 APR 2012 09:55AM EST

Print ISBN: 9780470612811

Online ISBN: 9781118229019

DOI: 10.1002/9781118229019

About this Book

This book covers various aspects of antibody mediated drug delivery systems - theoretical aspects, processing, viral and non-viral vectors, and fields where these systems find and /or are being evaluated for applications as therapeutics and diagnostic treatment. Chapters discuss actual applications of techniques used for formulation and characterization. Applications areas include cancer, pulmonary, ocular diseases; brain drug delivery; and vaccine delivery. The contributing authors represent over 10 different countries, covering recent developments happening around the globe.

Table of contents

    1. You have free access to this content
      Frontmatter (pages i–xxii)

    2. You have free access to this content
      Supplemental Images (pages c1–c12)

    3. Chapter 1

      Antibody-Mediated Drug Delivery Systems: General Review and Applications (pages 1–12)

      Navdeep Kaur, Karthikeyan Subramani and Yashwant Pathak

    4. Chapter 2

      Immunoliposomes for Cardiovascular Targeting (pages 13–33)

      Tatyana Levchenko, William Hartner and Vladimir P. Torchilin

    5. Chapter 3

      Antibody-Mediated Drug Delivery Systems for Breast Cancer Therapeutics (pages 35–55)

      Leonor Munoz Alcivar and Yashwant Pathak

    6. Chapter 4

      Development of Immunonconjugates for in Vivo Delivery: Cancer Diagnosis, Imaging, and Therapy (pages 57–81)

      Arutselvan Natarajan

    7. Chapter 5

      Mathematical Models of Anti-TNF Therapies and their Correlation with Tuberculosis (pages 83–104)

      Simeone Marino, Mohammad Fallahi-Sichani, Jennifer J. Linderman and Denise E. Kirschner

    8. Chapter 6

      Targeted Nanoparticles in Radiotherapy (pages 105–128)

      Misty Muscarella and Yashwant Pathak

    9. Chapter 7

      Electrically-Enhanced Delivery of Drugs and Conjugates for Cancer Treatment (pages 129–143)

      Arutselvan Natarajan, Luca Campana and Raji Sundararajan

    10. Chapter 8

      Characterization of Monoclonal Antibody Variants and Glycosylation (pages 145–167)

      Ting Zheng, Srinivasa Rao, Jeff Rohrer and Chris Pohl

    11. Chapter 9

      Antibody-Mediated Drug Delivery System for Lymphatic Targeting Treatment (pages 169–190)

      Fang Wu, Hong Ding and Zhirong Zhang

    12. Chapter 10

      Methods for Nanoparticle Conjugation to Monoclonal Antibodies (pages 191–207)

      Junling Li and Chin K. Ng

    13. Chapter 11

      Single-Use Systems in Animal Cell–Based Bioproduction (pages 209–228)

      William G. Whitford

    14. Chapter 12

      Immunoliposomes for Specific Drug Delivery (pages 229–266)

      Manuela Calin

    15. Chapter 13

      Gene Therapy Targeting Kidney Diseases: Routes and Vehicles (pages 267–277)

      Yoshitaka Isaka, Yoshitsugu Takabatake and Hiromi Rakugi

    16. Chapter 14

      Detection of Antibodies to Poly(Ethylene Glycol) Polymers Using Double-Antigen-Bridging Immunogenicity ELISA (pages 279–290)

      Yijuan Liu, Helen Reidler, Jing Pan, David Milunic, Dujie Qin, Dave Chen, Yli Remo Vallejo and Ray Yin

    17. Chapter 15

      Antibodies in Nanomedicine and Microimaging Methods (pages 291–349)

      Rakesh Sharma

    18. Chapter 16

      Methods for Polymeric Nanoparticle Conjugation to Monoclonal Antibodies (pages 351–363)

      Uyen Minh Le, Hieu Tran and Yashwant Pathak

    19. Chapter 17

      Plant-Derived Antibodies for Academic, Industrial, and Therapeutic Applications (pages 365–381)

      Slavko Komarnytsky and Nikolai Borisjuk

    20. Chapter 18

      Monoclonal Antibodies as Biopharmaceuticals (pages 383–389)

      Girish J. Kotwal

    21. Chapter 19

      Pulmonary Targeting of Nanoparticles and Monoclonal Antibodies (pages 391–405)

      Weiyuan Chang

    22. Chapter 20

      Antibody-Mediated Arthritis and New Therapeutic Avenues (pages 407–426)

      Kutty Selva Nandakumar

    23. Chapter 21

      Immunonanoparticles for Nuclear Imaging and Radiotherapy (pages 427–456)

      Oren Giladi and Simon Benita

    24. Chapter 22

      Monoclonal Antibodies in the Treatment of Asthma (pages 457–472)

      Glenn J. Whelan

    25. You have free access to this content
      Index (pages 473–505)

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