Plant Bioactives and Drug Discovery: Principles, Practice, and Perspectives

Plant Bioactives and Drug Discovery: Principles, Practice, and Perspectives

Editor(s): Valdir Cechinel-Filho

Published Online: 23 APR 2012 11:53AM EST

Print ISBN: 9780470582268

Online ISBN: 9781118260005

DOI: 10.1002/9781118260005

Series Editor(s): Binghe Wang

About this Book

An in-depth exploration of the applications of plant bioactive metabolites in drug research and development

Highlighting the complexity and applications of plant bioactive metabolites in organic and medicinal chemistry, Plant Bioactives and Drug Discovery: Principles, Practice, and Perspectives provides an in-depth overview of the ways in which plants can inform drug research and development. An edited volume featuring multidisciplinary international contributions from acclaimed scientists researching bioactive natural products, the book provides an incisive overview of one of the most important topics in pharmaceutical studies today.

With coverage of strategic methods of natural compound isolation, structural manipulation, natural products in clinical trials, quality control, and more, and featuring case studies on medicinal plants, the book serves as a definitive guide to the field of plant biodiversity as it relates to medicine. In addition, chapters on using natural products as drugs that target specific disease areas, including neurological disorders, inflammation, infectious diseases, and cancer, illustrate the myriad possibilities for therapeutic applications.

Wide ranging and comprehensive, Plant Bioactives and Drug Discovery also includes important information on marketing, regulations, intellectual property rights, and academic-industry collaboration as they relate to plant-based drug research, making it an essential resource for advanced students and academic and industry professionals working in biochemical, pharmaceutical, and related fields.

Table of contents

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    3. Chapter 5

      The Action of Plants and their Constituents on the Central Nervous System (pages 161–204)

      Fúlvio R. Mendes Giuseppina Negri, Joaquim M. Duarte-Almeida, Ricardo Tabach and Elisaldo A. Carlini

    4. Chapter 6

      The Role of Natural Products in Discovery of New Anti-Infective Agents with Emphasis on Antifungal Compounds (pages 205–239)

      Maximiliano Sortino, Marcos Derita, Laura Svetaz, Marcela Raimondi, Melina Di Liberto, Elisa Petenatti, Mahabir Gupta and Susana Zacchino

    5. Chapter 7

      Antiulcer Agents from Higher Plants (pages 241–262)

      Luiz C. Klein-Júnior, José R. Santin and Sérgio F. de Andrade

    6. Chapter 10

      Medicinal Plants and Pharmaceutical Technology (pages 359–393)

      Ruth M. Lucinda da Silva, Angélica G. Couto and Tania M. B. Bresolin

    7. Chapter 13

      Production of Bioactives Compounds: The Importance of Pictet–Spengler Reaction in the XXI Century (pages 453–487)

      Pilar Menendez, Ilaria D'Acquarica, Giuliano Delle Monache, Francesca Ghirga, Andrea Calcaterra, Marco Barba, Alberto Macone, Alberto Boffi, Alessandra Bonamore and Bruno Botta

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