Uremic Toxins

Uremic Toxins

Editor(s): Toshimitsu Niwa

Published Online: 17 SEP 2012 12:24PM EST

Print ISBN: 9781118135136

Online ISBN: 9781118424032

DOI: 10.1002/9781118424032

Series Editor(s): Dominic M. Desiderio, Nico M. M. Nibbering

About this Book

Reviews all the latest basic and clinical research findings

With contributions from leading international experts in the field, this book is dedicated to all facets of uremic toxins research, including low molecular weight solutes, protein-bound solutes, and middle molecules. Moreover, it covers everything from basic mass spectrometry research to the latest clinical findings and practices.

Uremic Toxins is divided into three sections:

  • Section One, Uremic Toxins, explores the definition, classification, listing, and mass spectrometric analysis of uremic toxins
  • Section Two, Selected Uremic Toxins, describes key uremic toxins, explaining chemical structures, metabolism, analytical methods, plasma levels, toxicity, clinical implications, and removal methods. Among the uremic toxins covered are indoxyl sulfate, asymmetric dimethylarginine, PTH, ß2-microglobulin, and AGEs
  • Section Three, Therapeutic Removal of Uremic Toxins, describes how uremic toxins can be removed by hemodialysis, peritoneal dialysis, and oral sorbent

All chapters are based on the authors' thorough review of the literature as well as their own personal laboratory and clinical experience. References at the end of each chapter provide a gateway to the literature in the field.

Reviewing all the latest basic and clinical research findings, Uremic Toxins will help bench scientists in nephrology advance their own investigations. It will also help clinicians take advantage of the latest tested and proven treatments for the management of chronic kidney disease.

Table of contents

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  1. Section 1: Uremic Toxins

    1. Chapter 2

      Classification and a List of Uremic Toxins (pages 13–33)

      Nathalie Neirynck, Rita de Smet, Eva Schepers, Raymond Vanholder and Griet Glorieux

  2. Section 2: Selected Uremic Toxins

    1. Chapter 5

      p-Cresyl Sulfate (pages 77–86)

      Anneleen Pletinck, Raymond Vanholder and Griet Glorieux

    2. Chapter 9

      Guanidino Compounds (pages 125–142)

      Sunny Eloot, Griet Glorieux, Peter Paul de Deyn and Raymond Vanholder

    3. Chapter 16

      β2-Microglobulin (pages 249–258)

      Suguru Yamamoto, Junichiro James Kazama, Hiroki Maruyama, Ichiei Narita and Fumitake Gejyo

    4. Chapter 17

      Cytokines (pages 259–277)

      Björn Anderstam, Bengt Lindholm and Peter Stenvinkel

    5. Chapter 20

      Oxidized Albumin (pages 305–314)

      Maurizio Bruschi, Giovanni Candiano, Laura Santucci and Gian Marco Ghiggeri

  3. Section 3: Therapeutic Removal of Uremic Toxins

    1. Chapter 22

      Therapeutic Removal of Uremic Toxins by Peritoneal Dialysis (pages 331–357)

      Malgorzata Debowska, Elvia García-López, Jacek Waniewski and Bengt Lindholm

    1. You have free access to this content
    1. You have free access to this content