Cancer and Inflammation Mechanisms: Chemical, Biological, and Clinical Aspects

Cancer and Inflammation Mechanisms: Chemical, Biological, and Clinical Aspects

Editor(s): Yusuke Hiraku, Shosuke Kawanishi, Hiroshi Ohshima

Published Online: 4 APR 2014 09:06PM EST

Print ISBN: 9781118160305

Online ISBN: 9781118826621

DOI: 10.1002/9781118826621

About this Book

A new perspective on the link between inflammation and cancer

Inflammation is the human body's normal biological response to threats in the modern world, as well as a defense against the harmful influence of pathogens, the environment, and poor nutrition. But what happens when the inflammatory response is triggered repeatedly and sustained for long periods of time? Cancer and Inflammation Mechanisms: Chemical, Biological, and Clinical Aspects discusses the mechanisms by which chronic inflammation can lead to cancer, the various causative agents, and possible prevention methods.

A compilation of the latest information coming out of the various fields of cancer research, this book provides a detailed look at inflammation-related carcinogenesis from the perspective of researchers at the forefront of the field. It takes an interdisciplinary approach to the topic, and provides comprehensive information about the major factors at work in inflammation, cancer, and the intersection of the two conditions. Topics include:

  • A general overview of inflammation-related cancer
  • The biochemistry of inflammation and its effects on DNA
  • Molecular biology and the role of microRNA in carcinogenesis
  • Specific causative agents including oncogenic viruses, asbestos, and nanomaterial
  • Anti-inflammatories, nutraceuticals, and other preventative measures

A deeper understanding of the mechanisms behind inflammation-related carcinogenesis can lead to better patient outcomes by improving diagnostics and prevention, as well as altering the approach to treatment. Cancer and Inflammation Mechanisms: Chemical, Biological, and Clinical Aspects provides the knowledge base researchers need to push the field forward.

Table of contents

    1. You have free access to this content
    2. Chapter 8

      Inflammasomes and Inflammation (pages 103–117)

      Kaiwen W. Chen, Ayanthi A. Richards, Alina Zamoshnikova and Kate Schroder

    3. Chapter 10

      MicroRNA and Inflammation-Related Cancer (pages 131–148)

      Zhaojian Gong, Zhaoyang Zeng, Pranab Behari Mazumder, Jian Ma, Ming Zhou, Xiayu Li, Xiaoling Li, Wei Xiong, Yong Li and Guiyuan Li

    4. Chapter 16

      Asbestos-Induced Chronic Inflammation and Cancer (pages 223–234)

      Andrea Napolitano, Sandro Jube, Giovanni Gaudino, Harvey I. Pass, Michele Carbone and Haining Yang

    5. Chapter 17

      Nanomaterials (pages 235–248)

      Yiqun Mo, Rong Wan, David J. Tollerud and Qunwei Zhang

    6. Chapter 18

      Inflammatory Pathways of Radiation-Induced Tissue Injury (pages 249–269)

      Danae A. Laskaratou, Ifigeneia V. Mavragani and Alexandros G. Georgakilas

    7. You have free access to this content
    8. You have free access to this content

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