Cyclic-Nucleotide Phosphodiesterases In The Central Nervous System: From Biology to Drug Discovery

Cyclic-Nucleotide Phosphodiesterases In The Central Nervous System: From Biology to Drug Discovery

Editor(s): Nicholas J. Brandon, Anthony R. West

Published Online: 7 MAR 2014 10:02PM EST

Print ISBN: 9780470566688

Online ISBN: 9781118836507

DOI: 10.1002/9781118836507

About this Book

This book reviews advances in understanding phosphodiesterases within the central nervous system and their therapeutic applications. A range of expert authors from both academia and industry describe these, then focus on the areas of greatest scientific and medical interest to provide more detailed coverage. Therapeutic and drug discovery applications are covered for diseases including Alzheimer's, Parkinson's, schizophrenia, erectile dysfunction, and spinal cord injuries. There is also a chapter on drug discovery tools such as in vitro assays and X-ray structures for medicinal chemistry studies.

Table of contents

    1. You have free access to this content
    2. Chapter 9

      Beyond Erectile Dysfunction: Understanding PDE5 Activity In The Central Nervous System (pages 223–246)

      Eva P.P. Bollen, Kris Rutten, Olga A.H. Reneerkens, Harry W.M. Steinbusch and Jos Prickaerts

    3. You have free access to this content
    4. You have free access to this content

SEARCH