Arsenic: Exposure Sources, Health Risks, and Mechanisms of Toxicity

Arsenic: Exposure Sources, Health Risks, and Mechanisms of Toxicity

Editor(s): J. Christopher States

Published Online: 30 OCT 2015 09:11PM EST

Print ISBN: 9781118511145

Online ISBN: 9781118876992

DOI: 10.1002/9781118876992

About this Book

This book illustrates the chemistry, toxicology, and health effects of arsenic using novel modeling techniques, case studies, experimental data, and future perspectives.

•    Covers exposure sources, health risks, and mechanisms of one of the most toxic minerals in the world
•    Helps readers understand potential health effects of arsenic, using population studies, mammalian and invertebrate models, and pharmacokinetic and toxicokinetic models
•    Discusses outcomes, epidemiology, real-life examples, and modes of action for arsenic-induced diseases, like lung cancer, diabetes, cardiovascular and pulmonary diseases, and immunotoxicity
•    Acts as a reference for toxicologists, environmental chemists, and risk assessors and includes up-to-date, novel modeling techniques for scientists
•    Includes future perspectives on special topics, like extrapolation from experimental models to human exposures, biomarkers for phenotypic anchoring, and pathology of chronic exposure

Table of contents

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  1. Part I: Fundamentals of Arsenic Exposure and Metabolism

  2. Part II: Epidemiology and Disease Manifestations of Arsenic Exposure

  3. Part III: Mechanisms of Toxicity

    1. Chapter 13

      Arsenic Interaction with Zinc Finger Motifs (pages 289–314)

      Laurie G. Hudson, Karen L. Cooper, Susan R. Atlas, Brenee S. King and Ke Jian Liu

    1. Chapter 15

      Genotoxicity (pages 347–367)

      Ana María Salazar and Patricia Ostrosky-Wegman

  4. Part IV: Models for Arsenic Toxicology and Risk Assessment

    1. You have free access to this content
    1. You have free access to this content

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