The Pancreas: An Integrated Textbook of Basic Science, Medicine, and Surgery, Second Edition

The Pancreas: An Integrated Textbook of Basic Science, Medicine, and Surgery, Second Edition

Editor(s): Hans G. Beger, Andrew L. Warshaw, Markus W. Büchler, Richard A. Kozarek, Markus M. Lerch, John P. Neoptolemos, Keiko Shiratori, David C. Whitcomb, Bettina M. Rau

Published Online: 4 FEB 2009

Print ISBN: 9781405146647

Online ISBN: 9781444300123

DOI: 10.1002/9781444300123

About this Book

The encyclopedic guide to the pancreas for practicing clinicians and surgeons

In the past decade extraordinary developments in diagnostic and therapeutic radiology and endoscopy have been coupled with major advances in surgical techniques and basic sciences. As a result the management of pancreatic disorders is now handled by a multidisciplinary team. This book shows you how to achieve superior patient management by taking the team approach to in-hospital care.


Fully revised and updated, this new edition of The Pancreas: An Integrated Textbook of Basic Science, Medicine and Surgery details the latest knowledge on genetics and molecular biological background in terms of anatomy, physiology, pathology, and pathophysiology for all known pancreatic disorders. The Editor and author team are leading pancreatologists of high international repute and they present global best-practice and evidence-based knowledge in this comprehensive reference.


A timely section on early and late outcome data considers the benefits of management including chemotherapy and immune therapy. Incorporating evidence-based data, the book also focuses on early diagnosis, limited surgical treatment, oncology, treatment results and the option of transplantation.


This new edition contains more than 400 illustrations, line drawings and radiographs to provide a step-by-step approach to endoscopic techniques and surgical procedures. With The Pancreas:An Integrated Textbook of Basic Science, Medicine and Surgery, Second Edition, you can achieve a greater understanding of current diagnostic, medical and surgical treatment principles in one authoritative reference point.

Table of contents

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    1. You have free access to this content
  1. Section One: Anatomy of the Pancreas

    1. Chapter 2

      The History of the Pancreas (pages 7–41)

      Irvin M. Modlin, Manish C. Champaneria, Anthony K. C. Chan, Mark Kidd and Geeta N. Eick

  2. Section Two: Physiology of Pancreatic Functions

  3. Section Three: Acute Pancreatitis

    1. Chapter 26

      Treatment of Acute Pancreatitis (pages 273–287)

      Paul Georg Lankisch, Mark Topazian and Henry J. Schiller

    2. Chapter 33

      Management of Fluid Collections in Acute Pancreatitis (pages 344–355)

      Gregory Stringfellow, Eric Vansonnenberg, Giovanna Casola, Gerhard R. Wittich, Sridhar Shankar and Ray Shamos

  4. Section Three: Acute pancreatitis

    1. Chapter 29

      Surgical Management of Necrotizing Pancreatitis (pages 308–320)

      Bettina M. Rau, Hans G. Beger, Raymond Aerts, Freddy M. Penninckx, J. Rubén Rodríguez, Carlos Fernández-del Castillo and Andrew L. Warshaw

  5. Section Four: Chronic Pancreatitis

    1. Chapter 38

      Fibrogenesis of the Pancreas: The Role of Stellate Cells (pages 383–392)

      Max G. Bachem, Shaoxia Zhou, Wilhelm Schneiderhan and Marco Siech

    2. Chapter 39

      Epidemiology and Pathophysiology of Alcoholic Chronic Pancreatitis (pages 393–402)

      Stephen J. Pandol, Aurelia Lugea, Anna S. Gukovskaya and Ilya Gukovsky

    3. Chapter 52

      Medical Treatment of Chronic Pancreatitis (pages 504–526)

      Joachim Mössner, Peter Layer, Jutta Keller, Daniel K. Mullady, Stephen J. D. Oí'Keefe, Nathan Howes, William Greenhalf and Michael G. T. Raraty

    4. Chapter 54

      Strategies for Surgical Treatment of Chronic Pancreatitis (pages 537–560)

      Hans G. Beger, Frank Gaunsauge, Michael Schwarz, Bertram Poch, Oscar J. Hines, Howard A. Reber, Bettina M. Rau, Kaye M. Reid-Lombardo, Michael B. Farnell, Michael G. Sarr, Colin J. McKay and Peter Wysocki

  6. Section Five: Neoplastic Lesions of Exocrine Tissue: Pancreatic Cancer

    1. Chapter 57

      Epidemiology of Pancreatic Cancer (pages 571–582)

      Nicholas Alexakis, Paula Ghaneh and John P. Neoptolemos

    2. Chapter 59

      Familial Pancreatic Cancer (pages 591–600)

      William Greenhalf, Louis J. Vitone and John P. Neoptolemos

    3. Chapter 64

      Screening of Hereditary Pancreatic Cancer Families (pages 636–642)

      Christopher Carlson, William Greenhalf and Teresa A. Brentnall

    4. Chapter 65

      Clinical Assessment and Staging of Pancreatic Cancer (pages 643–647)

      J. Ruben Rodriguez, Andrew L. Warshaw and Carlos Fernández-Del Castillo

    5. Chapter 76

      Neoadjuvant Treatment of Pancreatic Cancer: Borderline-Resectable Disease (pages 727–740)

      Gauri Varadhachary, Christopher H. Crane, Eric P. Tamm, Huamin Wang, Robert A. Wolff and Douglas B. Evans

    6. Chapter 79

      Management of Cancer Pain (pages 757–764)

      Sergio Pedrazzoli, Claudio Pasquali, Cosimo Sperti and Francesca Avogaro

    7. Chapter 81

      Management of Cancer Recurrence (pages 772–775)

      Helmut Friess, Jörg Kleeff and Markus W. Büchler

    8. Chapter 82

      Survival and Late Morbidity after Resection of Pancreatic Cancer (pages 776–784)

      Osamu Ishikawa, Hiroaki Ohigashi, Hidetoshi Eguchi, Yo Sasaki, Terumasa Yamada and Shingi Imaoka

  7. Section Six: Endocrine Tumors of the Pancreas

    1. Chapter 84

      Islet Cell Tumors (pages 794–801)

      Peter E. Goretzki and Hans-Dietrich Röher

    2. Chapter 85

      Pancreatic Endocrine Tumors in Multiple Endocrine Neoplasia Syndrome (pages 802–812)

      Elisabeth Spilcke-Liss, Peter Simon, Markus M. Lerch and Henri Wallaschofski

    3. Chapter 86

      Nonfunctioning Endocrine Tumors (pages 813–817)

      Hodaka Amano, Tadahiro Takada, Fumihiko Miura, Takehide Asano, Masahiro Yoshida, Naoyuki Toyota, Keita Wada, Takahiro Isaka, Naoyuki Tamura and Kenichiro Kato

  8. Section six: Endocrine Tumors of the Pancreas

    1. Chapter 91

      Long-Term Outcome after Treatment of Endocrine Tumors (pages 845–852)

      Henning Dralle, Andreas Machens, Michael Brauckhoff and Oliver Gimm

  9. Section Seven: Periampullary Tumors

  10. Section Eight: Other Tumors of the Pancreas

    1. Chapter 98

      Diagnostic Imaging of Cystic Tumors (pages 912–917)

      Masao Tanaka, Kiichiro Kobayashi, Reiko Tanabe and Koji Yamaguchi

  11. Section Nine: Transplantation of the Pancreas

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