Mycobacteria: Molecular Biology and Virulence

Mycobacteria: Molecular Biology and Virulence

Editor(s): Colin Ratledge, Jeremy Dale

Published Online: 17 APR 2009

Print ISBN: 9780632053049

Online ISBN: 9781444311433

DOI: 10.1002/9781444311433

About this Book

Tuberculosis continues to kills more people than any other single infective agent. The resurgence of the disease in many countries has produced a heightened awareness of the threat posed by mycobacterial infections. At the same time, there has been an explosion of knowledge of the fundamental properties of mycobacteria, most notably the determination of the complete genome sequence of Mycobacterium tuberculosis.

This book provides an up-to-date account of these developments in the molecular biology and immunology of mycobacteria, coupled with allied advances of a more applied nature, such as the use of molecular techniques for diagnosis and epidemiological investigations. With chapters contributed from an international team of experts, it will not only be an essential reference text for the expanding mycobacterial research community, but also will find a prominent place on the shelves of clinicians, infectious disease and public health specialists, diagnostic laboratories, postgraduate students and indeed anyone concerned with the management and investigation of outbreaks of tuberculosis.


  • Comprehensively covers recent advances in the molecular biology of the mycobacteria.
  • First book to be published on this subject since the publishing of the complete genome for the tubercle bacillus (M. tuberculosis).
  • Coincides with a worldwide resurgence of tuberculosis.

Table of contents

    1. You have free access to this content
    2. You have free access to this content
    3. Chapter 1

      Recombination (pages 1–16)

      Graham R. Stewart and Johnjoe McFadden

    4. Chapter 5

      Genomics of Mycobacterium Tuberculosis and Mycobacterium Leprae (pages 93–109)

      Stephen V. Gordon, Karin Eiglmeier, Roland Brosch, Thierry Garnier, Nadine Honoré, Bart G. Barrell and Stewart T. Cole

    5. Chapter 10

      Immunodiagnosis of Mycobacterial Infection (pages 180–197)

      Graham H. Bothamley, David Catty, Richard Clifton-Hadley, Frank Griffin, Glyn Hewinson and John Pollock

    6. Chapter 18

      Mycobacterial Antigens (pages 356–370)

      Jelle Thole, Riny Janssen and Douglas Young

    7. You have free access to this content

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