Leukemias: Principles and Practice of Therapy

Leukemias: Principles and Practice of Therapy

Editor(s): Stefan Faderl, Hagop Kantarjian

Published Online: 4 JAN 2011 04:42AM EST

Print ISBN: 9781405182355

Online ISBN: 9781444327359

DOI: 10.1002/9781444327359

About this Book

Edited by experts from one of the world's largest leukemia centers, this book provides information on the biology of the variety of leukemic disorders, up-to-date diagnostic testing and many new developments in therapy. Chapters covering new treatments present an outlook for the future and explain the rationale for ongoing clinical trials.

Topics include:

  • Targeted therapy, e.g. tyrosine kinase inhibitors (Flt3, Aurora kinase inhibitors, kit inhibitors, BCR-ABL inhibitors)
  • Ras inhibitors
  • Epigenetic therapy (hypomethylaters and histone deacetylase inhibitors)
  • Lenalidomide analogs
  • New chemotherapy drugs, e.g. clofarabine, cloretazine, sapacitabine, forodesine
  • Combinations of chemotherapy with kinase inhibitors (e.g. ALL induction protocols in combination with dasatinib or imatinib)
  • New monoclonal antibodies (lumiliximab, humaxCD20, anti-CD40)
  • Thrombopoietic agents

Leukemias: Principles and Practice of Therapy

  • Includes practical information to guide you in challenging situations, such as treatment of elderly patients, pregnancy, relapsed and refractory disease
  • Incorporates chapters on supportive care and pharmacologic information about the most frequently used drugs in this area

Table of contents

    1. You have free access to this content
    2. You have free access to this content
    3. Chapter 3

      Traditional Diagnostic Approaches (pages 29–42)

      Hartmut Koeppen, Carlos E. Bueso-Ramos and Sergej N. Konoplev

    4. You have free access to this content

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