Parkinson's Disease: Non-Motor and Non-Dopaminergic Features

Copyright © 2011 Blackwell Publishing Ltd

Parkinson's Disease: Non-Motor and Non-Dopaminergic Features

Editor(s): C. Warren Olanow, Fabrizio Stocchi, Anthony E. Lang

Published Online: 27 JUN 2011 02:50AM EST

Print ISBN: 9781405191852

Online ISBN: 9781444397970

DOI: 10.1002/9781444397970

About this Book

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About The Product

Parkinson's Disease has traditionally been seen as a movement disorder, and diagnosed by the development of tremor. However, we are beginning to understand that the disease manifests itself in many ways, and that earlier diagnosis might be possible through non-tremor symptoms. This textbook aims to tell the full story of non-motor and non-dopaminergic features of Parkinson's Disease.

Table of contents

    1. You have free access to this content
      Front Matter (pages i–x)

    2. You have free access to this content
      Colour Plates (pages c1–c8)

    3. Chapter 1

      The Dopaminergic and Non-Dopaminergic Features of Parkinson's Disease (pages 1–6)

      C. Warren Olanow, Fabrizio Stocchi and Anthony E. Lang

    4. Chapter 2

      Neuropathologic Involvement of the Dopaminergic Neuronal Systems in Parkinson's Disease (pages 7–14)

      Daniel P. Perl

    5. Chapter 3

      Non-Dopaminergic Pathology of Parkinson's Disease (pages 15–31)

      Heiko Braak and Kelly Del Tredici

    6. Chapter 4

      Functional Anatomy of the Motor and Non-Motor Circuitry of the Basal Ganglia (pages 32–55)

      Yoland Smith

    7. Chapter 5

      Functional Organization of the Basal Ganglia: Dopaminergic and Non-Dopaminergic Features (pages 56–69)

      Carlos Juri, Maria C. Rodriguez-Oroz and Jose A. Obeso

    8. Chapter 6

      Anatomy and Physiology of Limbic System Dysfunction in Parkinson's Disease (pages 70–78)

      Anthony A. Grace

    9. Chapter 7

      Animal Models of Parkinson's Disease: The Non-Motor and Non-Dopaminergic Features (pages 79–92)

      Katherine E. Soderstrom, Shilpa Ramaswamy, C. Warren Olanow and Jeffrey H. Kordower

    10. Chapter 8

      The Emerging Entity of Pre-Motor Parkinson's Disease (pages 93–104)

      J. William Langston

    11. Chapter 9

      Functional Imaging Studies in Parkinson's Disease: The Non-Dopaminergic Systems (pages 105–110)

      A. Jon Stoessl

    12. Chapter 10

      Assessment of Non-Motor Features of Parkinson's Disease: Scales and Rating Tools (pages 111–125)

      Christopher G. Goetz and Cristina Sampaio

    13. Chapter 11

      Clinical Trial Measures of the Non-Motor Features of Parkinson's Disease (pages 126–133)

      Karl Kieburtz

    14. Chapter 12

      Clinical Features of Dementia Associated with Parkinson's Disease and Dementia with Lewy Bodies (pages 134–144)

      David J. Burn

    15. Chapter 13

      Neuropsychologic Features of Parkinson's Dementias (pages 145–152)

      Leonardo Cruz de Souza, Virginie Czernecki and Bruno Dubois

    16. Chapter 14

      Neuropathology of Dementia in Parkinson's Disease (pages 153–162)

      Dennis W. Dickson and Carolyn F. Orr

    17. Chapter 15

      Treatment of Dementia Associated with Parkinson's Disease (pages 163–169)

      Murat Emre

    18. Chapter 16

      Psychosis in Parkinson's Disease (pages 170–182)

      Joseph H. Friedman

    19. Chapter 17

      Depression in Parkinson's Disease (pages 183–192)

      Tiffini Voss and Irene Hegeman Richard

    20. Chapter 18

      Anxiety Syndromes and Panic Attacks (pages 193–201)

      Daniel Weintraub and Staci Hoops

    21. Chapter 19

      Dopamine Dysregulation Syndrome (pages 202–214)

      Sean S. O'Sullivan and Andrew J. Lees

    22. Chapter 20

      Neurobiology of Impulse Control Disorders in Parkinson's Disease (pages 215–232)

      Thomas D. L. Steeves, Janis Miyasaki, Anthony E. Lang and Antonio P. Strafella

    23. Chapter 21

      Sleep Disorders in Parkinson's Disease (pages 233–239)

      Friederike Sixel-Döring and Claudia Trenkwalder

    24. Chapter 22

      Neuronal Mechanisms of REM Sleep and their Role in REM Sleep Behavior Disorder (pages 240–245)

      Jun Lu and Clifford B. Saper

    25. Chapter 23

      REM Sleep Behavior Disorder and Neurodegenerative Disorders (pages 246–256)

      Mark W. Mahowald, Carlos H. Schenck and Michel A. Cramer Bornemann

    26. Chapter 24

      Gastrointestinal and Swallowing Disturbances in Parkinson's Disease (pages 257–273)

      Ronald F. Pfeiffer

    27. Chapter 25

      Bladder Dysfunction in Parkinson's Disease and Other Parkinsonism (pages 274–283)

      Fabrizio Stocchi, Margherita Torti, Giovanni Palleschi and Antonio Carbone

    28. Chapter 26

      Orthostatic Hypotension in Parkinson's Disease (pages 284–295)

      Uday Muthane and Christopher J. Mathias

    29. Chapter 27

      Sexual Dysfunction (pages 296–303)

      Kimberly Pargeon, Karen Anderson and William J. Weiner

    30. Chapter 28

      Olfactory Dysfunction (pages 304–314)

      John E. Duda and Matthew B. Stern

    31. Chapter 29

      Pain and Paresthesia in Parkinson's Disease (pages 315–332)

      Shen-Yang Lim and Andrew H. Evans

    32. Chapter 30

      Restless Legs Syndrome and Akathisia in Parkinson's Disease (pages 333–345)

      Alex Iranzo and Cynthia L. Comella

    33. Chapter 31

      Speech and Voice Disorders in Parkinson's Disease (pages 346–360)

      Lorraine Ramig, Cynthia Fox and Shimon Sapir

    34. Chapter 32

      Gait, Postural Instability, and Freezing (pages 261–373)

      Yvette A. M. Grimbergen, Arlène D. Speelman, Marjolein A. van der Marck, Yvonne Schoon and Bastiaan R. Bloem

    35. Chapter 33

      Orthopedic Complications of Parkinson's Disease (pages 374–386)

      Joseph Rudolph and Michele Tagliati

    36. Chapter 34

      Other Non-Motor Symptoms of Parkinson's Disease (pages 387–393)

      Mark J. Edwards and Kailash P. Bhatia

    37. Chapter 35

      Overview of the Medical Treatment of the Non-Motor and Non-Dopaminergic Features of Parkinson's Disease (pages 394–408)

      Mark Stacy and Joseph Jankovic

    38. Chapter 36

      Surgery for Non-Dopaminergic and Non-Motor Features of Parkinson's Disease (pages 409–415)

      Brian J. Snyder and Andres M. Lozano

    39. Chapter 37

      Effects of Exercise on Basal Ganglia Function in Parkinson's Disease and Its Animal Models (pages 416–431)

      Giselle M. Petzinger, Beth E. Fisher, Charlie K. Meshul, John P. Walsh, Garnik Akopian and Michael W. Jakowec

    40. Chapter 38

      Non-Dopaminergic Approaches to the Treatment of Parkinson's Disease (pages 432–454)

      Susan H. Fox and Jonathan M. Brotchie

    41. Chapter 39

      Prospects for Neuroprotective Therapies that can Modulate Non-Dopaminergic Features in Parkinson's Disease (pages 455–461)

      C. Warren Olanow and Anthony E. Lang

    42. You have free access to this content
      Index (pages 463–474)

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