Muscle Aging, Inclusion-Body Myositis and Myopathies

Muscle Aging, Inclusion-Body Myositis and Myopathies

Editor(s): Valerie Askanas, W. King Engel

Published Online: 19 DEC 2011 08:49AM EST

Print ISBN: 9781405196468

Online ISBN: 9781444398311

DOI: 10.1002/9781444398311

About this Book

Muscle weakness with ageing is almost inevitable, generally beginning to manifest beyond the age of 40, and is usually unstoppable. It can lead to reduced mobility, increased risk of falling, injury, and even death. But "you're just getting old" is not a sufficient diagnosis. Specific causes of neuromuscular symptoms may explain progressive muscle weakness, and should be investigated for potential treatment.

Muscle Ageing, Inclusion-Body Myositis and Myopathies explores the clinical and pathological expression of muscle weakness in aging persons. Case studies demonstrate how physicians can more accurately diagnose weakening elderly patients and make better management decisions. 

It also explores sporadic inclusion-body myositis and hereditary inclusion-body myopathies. The former, the most common progressive muscle disease in the over 50s, is frequently under-diagnosed and, with the increasing population of aged individuals, is presenting a greater challenge. This disease of muscle has pathological similarities with the well-known Alzheimer and Parkinson brain diseases.

Edited and written by a leading international cast of authors, Muscle Ageing, Inclusion-Body Myositis and Myopathies provides a state-of-the-art guide to ageing-associated neuromuscular disorders. It should be in the hands of all those involved in the care of aging and muscle-weakened patients.

  
Titles of Related Interest
Neuromuscular Disorders
Tawil and Vennance (eds); ISBN 978-0-470-65456-9

European Handbook of Neurological Management, Vol 1, 2e
Gilhus, Barnes, Brainin (eds); ISBN 978-1-4051-8533-2

European Handbook of Neurological Management, Vol 2, 2e
Gilhus, Barnes, Brainin (eds); ISBN 978-1-4051-8534-9

Table of contents

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    1. You have free access to this content
  1. Part 1: Muscle Aging

  2. Part 2: Sporadic Inclusion-Body Myositis

  3. Part 3: Hereditary Inclusion-Body Myopathies

    1. Chapter 15

      Clinical Spectrum of VCP Myopathy, Paget Disease, and fronTotemporal Dementia: Experimental Models and Potential Treatments (pages 219–229)

      Virginia E. Kimonis, Eric Dec, Mallikarjun Badadani, Angele Nalbandian, Jouni Vesa, Vincent Caiozzo, Douglas Wallace, Barbara Martin, Charles Smith and Giles D. Watts

    1. You have free access to this content

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